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RXFP1

RXFP1,即松弛素家族肽受體1,別名LGR7、RXFPR1。RXFP1屬于G蛋白偶聯(lián)7次跨膜受體超家族中富含亮氨酸重復(fù)的亞組,是蛋白質(zhì)激素松弛素的受體。RXFP1通過與松弛素結(jié)合,激活G蛋白信號傳導(dǎo)途徑,從而在精子活力、懷孕和分娩中發(fā)揮重要作用。RXFP1在調(diào)節(jié)生殖系統(tǒng)、心血管系統(tǒng)以及抗纖維化等方面具有關(guān)鍵作用,其表達(dá)減少可能在子宮內(nèi)膜異位癥中起作用。RXFP1的激活還可以降低血管阻力和潛在的肺壓,增加心輸出量,增強(qiáng)腎、肺和肝臟重要中央血管床的灌注。

熱銷產(chǎn)品

RXFP1 Antibody (CSB-PA875715LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA875715LA01HU

Immunofluorescence staining of Hela cells with CSB-PA875715LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

RXFP1 Antibodies

RXFP1 for Homo sapiens (Human)

RXFP1 Proteins

RXFP1 Proteins for Pongo abelii (Sumatran orangutan)

RXFP1 Proteins for Rattus norvegicus (Rat)

RXFP1 Proteins for Mus musculus (Mouse)

RXFP1 Proteins for Homo sapiens (Human)