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RUVBL2

RUVBL2,別名RVB2、TIH2、ECP51、TIP48、CGI-46、ECP-51、INO80J、REPTIN、TIP49B、TAP54-beta,在人類細胞中廣泛表達,屬于AAA+ATPase家族成員。RUVBL2的作用機制涉及其ATP酶活性,參與多種細胞過程,包括染色質重塑、轉錄調控、葡萄糖轉運以及大分子復合物的組裝。RUVBL2還起到轉錄調控的作用,通過調節與軸突生成和突觸小泡相關的基因表達來調控突觸可塑性和突觸傳遞,進而影響食欲和體重控制。RUVBL2與多種疾病相關,包括脊髓性肌肉萎縮、遠端遺傳性運動神經元病、先天性角化不良等。

熱銷產品

Recombinant Human RuvB-like 2 (RUVBL2) (CSB-EP897459HU)

驗證數據

CSB-EP897459HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

RUVBL2 Antibody (CSB-PA897459LA01HU)

驗證數據

CSB-PA897459LA01HU

Western Blot
Positive WB detected in: K562 whole cell lysate, HepG2 whole cell lysate, Rat liver tissue, Mouse brain tissue
All lanes: RUVBL2 antibody at 2.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 52, 47 kDa
Observed band size: 52 kDa

CSB-PA897459LA01HU

IHC image of CSB-PA897459LA01HU diluted at 1:600 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA897459LA01HU

IHC image of CSB-PA897459LA01HU diluted at 1:600 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

RUVBL2 Antibodies

RUVBL2 for Homo sapiens (Human)

RUVBL2 Proteins

RUVBL2 Proteins for Homo sapiens (Human)



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