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RAG1

Vis a protein in humans that is encoded by RAG1 gene. Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment.

RAG1 Proteins

RAG1 Proteins for Oryza sativa subsp. japonica (Rice)

RAG1 Proteins for Mus musculus (Mouse)

RAG1 Proteins for Homo sapiens (Human)

RAG1 Proteins for Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)

RAG1 Proteins for Oryctolagus cuniculus (Rabbit)

RAG1 Proteins for Gallus gallus (Chicken)

RAG1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

RAG1 Proteins for Sus scrofa (Pig)

RAG1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

RAG1 Proteins for Ginglymostoma cirratum (Nurse shark)

RAG1 Proteins for Xenopus laevis (African clawed frog)



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