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RAB8A

Ras-related protein Rab-8A is a protein in humans that is encoded by RAB8A gene. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

RAB8A Antibodies

RAB8A for Homo sapiens (Human)

RAB8A Proteins

RAB8A Proteins for Rattus norvegicus (Rat)

RAB8A Proteins for Mus musculus (Mouse)

RAB8A Proteins for Homo sapiens (Human)

RAB8A Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

RAB8A Proteins for Bos taurus (Bovine)

RAB8A Proteins for Dictyostelium discoideum (Slime mold)

RAB8A Proteins for Gallus gallus (Chicken)

RAB8A Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

RAB8A Proteins for Pongo abelii (Sumatran orangutan)



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