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PVR

PVR,全名為脊髓灰質炎病毒受體,是一種跨膜糖蛋白,屬于nectin家族。它有多種別名,如CD155、HVED、PVS等。PVR蛋白在細胞粘附、信號傳導和免疫反應中發揮重要作用。在脊髓灰質炎病毒感染中,PVR作為病毒受體,介導病毒進入細胞。此外,PVR還與多種疾病相關,如腫瘤、自身免疫疾病等。目前,針對PVR的藥物研發主要集中在開發抗腫瘤藥物,如針對PVR的抗體藥物,以抑制腫瘤生長和轉移。

熱銷產品

Recombinant Human Poliovirus receptor (PVR) (I340M), partial (Active) (CSB-MP019093HU(M))

驗證數據

CSB-MP019093HU(M)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP019093HU(M)

Activity
FACS assay shows that Human PVR can bind to HEK293F cell overexpressing human TIGIT.

PVR Recombinant Monoclonal Antibody (CSB-RA567944A0HU)

驗證數據

CSB-RA567944A0HU

Western Blot
Positive WB detected in: A549 whole cell lysate
All lanes: Poliovirus Receptor antibody at 1:500
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 70 kDa
Observed band size: 70 kDa

CSB-RA567944A0HU

IHC image of CSB-RA567944A0HU diluted at 1:50 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.42% DAB.

PVR Antibodies

PVR for Homo sapiens (Human)

PVR Proteins

PVR Proteins for Homo sapiens (Human)

PVR Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

PVR ELISA Kit

PVR ELISA Kit for Homo sapiens (Human)



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