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PPIP5K2

Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 is a protein in humans that is encoded by PPIP5K2 gene. Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4.

PPIP5K2 Proteins

PPIP5K2 Proteins for Homo sapiens (Human)

PPIP5K2 Proteins for Xenopus laevis (African clawed frog)

PPIP5K2 Proteins for Pongo abelii (Sumatran orangutan)

PPIP5K2 Proteins for Mus musculus (Mouse)



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