在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

POU5F1

POU5F1 is also known as Oct3, Oct4, Otf3 or NF-A3. It is encoded by the POU5F1 gene, which belongs to POU transcription factor family, class-5 subfamily.

POU5F1 gene and located on the human chromosome 6p21.3. It has multiple transcription initiation sites, leading to a diversity of POU5F1 proteins. There are four protein subtypes (Oct4A, oct4b-190, oct4b-265 and oct4b-164).

Oct4 is mainly expressed in embryonic stem cells, embryonic germ cells and embryonic/germ cell tumors, but is less expressed in adult tissues. In embryonic germ cells, Oct4 expression is down-regulated as cells differentiate.

Oct4 consists of three domains: N-transcription domain, POU binding domain and C-transcription domain. POU binding domain is a conserved DNA binding domain that binds to DNA containing an octamer motif to regulate transcription of downstream target genes.

Oct4 participates in the regulation of several signaling pathways, including transforming growth factor (TGF) beta pathway, fibroblast growth factor (FGF) pathway, phosatidylinositol-3-kinase (PI3K) pathway, Wnt pathway, etc.

POU5F1 regulates the expression of target genes by combining with octamer motif (5'-ATTTGCAT-3') in promoter or enhancer regions

POU5F1 is critical for early embryogenesis and for embryonic stem cell pluripotency. In addition, POU5F1 may be involved in the occurrence and development of malignant tumors.

For more information, click here.

CSB-MA018403A0m (Oct4 Monoclonal Antibody) is a product of CUSABIO. The product can be used in human, rat and mouse. It has been validated in various applications, including ELISA, WB, IHC, IF and FC.

POU5F1 Antibodies

POU5F1 for Homo sapiens (Human)

POU5F1 Proteins

POU5F1 Proteins for Mus musculus (Mouse)

POU5F1 Proteins for Bos taurus (Bovine)

POU5F1 Proteins for Macaca mulatta (Rhesus macaque)

POU5F1 Proteins for Pan troglodytes (Chimpanzee)

POU5F1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

POU5F1 Proteins for Sus scrofa (Pig)

POU5F1 Proteins for Homo sapiens (Human)



主站蜘蛛池模板: 婷婷色婷婷开心五月| 我的性奴的肉玩具1一17心奴| 亚洲毛片αv无线播放一区| 亚洲国产中文字幕在线视频综合| 亚洲精品tv久久久久久久久久| 成人免费无遮挡在线播放| 色欲天天婬色婬香视频综合网| 欧美午夜精品久久久久免费视| 亚洲一卡二卡三卡四卡| 99国产精品久久久久久久成人| 欧美99久久无码一区人妻a片| 亚洲不卡一卡2卡三卡4卡5卡| 亚洲色精品三区二区一区| 无码人妻av一二区二区三区| 日本高清熟妇老熟妇| 色偷偷www.8888在线观看 | 日韩一区二区三区无码影院| 老司机导航亚洲精品导航| 免费无码作爱视频| 欧美黑吊大战白妞| 中文字幕人妻中文av不卡专区 | 国产精品黄页免费高清在线观看 | 婷婷开心激情综合五月天| 国厂精品114福利电影免费| 97在线观看播放| 成人国产精品一区二区网站公司| 亚洲卡1卡2卡新区网站| 国产成人人综合亚洲欧美丁香花| 亚洲女同一区二区| 国产av天堂无码一区二区三区| 免费的av网站在线观看国产精品| 欧美丰满老熟妇乱叫| 国产成人a∨激情视频厨房| 天天噜日日噜狠狠噜免费| 亚洲一区二区三区在线观看网站 | 久久一日本综合色鬼综合色| 成人欧美一区二区三区的电影| 狠狠综合亚洲综合亚洲色| 欧美成人午夜性视频| 中国少妇内射xxxx狠干| 无码人妻丰满熟妇区毛片18|