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PDK1

[Pyruvate dehydrogenase is a protein in humans that is encoded by PDK1 gene. Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.

PDK1 Antibodies

PDK1 for Homo sapiens (Human)

PDK1 Proteins

PDK1 Proteins for Homo sapiens (Human)

PDK1 Proteins for Rattus norvegicus (Rat)

PDK1 Proteins for Mus musculus (Mouse)

PDK1 Proteins for Drosophila melanogaster (Fruit fly)

PDK1 Proteins for Mus musculus(Mouse)