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PCBP2

PCBP2,即聚(rC)結合蛋白2,別名HNRPE2、HNRNPE2、hnRNP-E2。PCBP2是一種RNA結合蛋白,含有三個K同源(KH)結構域,這些結構域參與RNA結合。PCBP2涉及多種細胞途徑,包括mRNA穩定性和翻譯控制。PCBP2與PCBP-1一起,通過與IRES的莖環IV的序列特異性相互作用,作為脊髓灰質炎病毒RNA的翻譯共激活因子,促進脊髓灰質炎病毒RNA復制。PCBP2還參與15-脂氧合酶mRNA、人乳頭瘤病毒16型L2 mRNA和甲型肝炎病毒RNA的翻譯控制。PCBP2在多種生理過程中發揮作用,包括基因表達的轉錄和轉錄后調控,以及在病毒感染中的RNA復制和翻譯調控。PCBP2還與多種疾病相關,包括前顳葉癡呆和慢性髓系白血病。

熱銷產品

Recombinant Human Poly (rC)-binding protein 2 (PCBP2) (CSB-EP622995HU)

驗證數據

CSB-EP622995HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PCBP2 Antibody (CSB-PA622995LA01HU)

驗證數據

CSB-PA622995LA01HU

Western Blot
Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate
All lanes: PCBP2 antibody at 5.3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 39, 35, 36, 34 kDa
Observed band size: 43 kDa

CSB-PA622995LA01HU

IHC image of CSB-PA622995LA01HU diluted at 1:200 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA622995LA01HU

IHC image of CSB-PA622995LA01HU diluted at 1:200 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

PCBP2 Antibodies

PCBP2 for Homo sapiens (Human)

PCBP2 Proteins

PCBP2 Proteins for Homo sapiens (Human)



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