NOS3
NOS3，即一氧化氮合酶3，別名NOS III、NOS type III、NOS3。它是一種由NOS3基因編碼的蛋白質(zhì)，屬于一氧化氮合酶家族成員之一。NOS3主要在血管內(nèi)皮細(xì)胞中表達(dá)，對血管舒張和血液流動的調(diào)節(jié)具有重要作用。NOS3的作用機(jī)制是通過催化L-精氨酸的氧化反應(yīng)，生成一氧化氮（NO）和L-瓜氨酸。一氧化氮是一種關(guān)鍵的血管舒張因子，能夠激活鳥苷酸環(huán)化酶，增加cGMP水平，從而誘導(dǎo)血管平滑肌細(xì)胞的松弛。此外，NOS3生成的NO還參與了血小板聚集、白細(xì)胞黏附以及血管新生等生理過程。NOS3不僅參與了血管內(nèi)皮的保護(hù)作用，還與多種疾病的發(fā)生發(fā)展密切相關(guān)。例如，NOS3的多態(tài)性與冠狀動脈痙攣的易感性有關(guān)，其功能受損可能導(dǎo)致高血壓等心血管疾病。此外，NOS3在腫瘤的發(fā)展和轉(zhuǎn)移中也扮演著重要角色，其表達(dá)水平的變化可能影響腫瘤血管生成和腫瘤細(xì)胞的侵襲性。因此，NOS3是心血管疾病和腫瘤研究中的一個重要靶點。
熱銷產(chǎn)品
NOS3 Monoclonal Antibody (CSB-MA000326)
驗證數(shù)據(jù)
Western blot analysis of Rat Heart Tissue, diluted at 1:1000.
NOS3 Antibodies
NOS3 for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA16579A0Rb | Nos3 Antibody | Rat | ELISA |
| CSB-PA16579C0Rb | Nos3 Antibody, FITC conjugated | Rat | |
| CSB-PA16579B0Rb | Nos3 Antibody, HRP conjugated | Rat | ELISA |
NOS3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA279955 | Phospho-NOS3 (Ser1177) Antibody | Human,Mouse,Rat | ELISA,IHC,IF |
| CSB-PA043009 | NOS3 (Ab-1177) Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA064019 | NOS3 (Ab-495) Antibody | Human,Mouse,Rat | ELISA,IF |
| CSB-PA921078 | Phospho-NOS3 (Ser615) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA000659 | Phospho-NOS3 (S1177) Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA003466 | NOS3 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA003467 | NOS3 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA020134 | Phospho-NOS3 (T494) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA020135 | Phospho-NOS3 (S615) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA020136 | NOS3 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA020137 | NOS3 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
NOS3 for H, M, R
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-MA000326 | NOS3 Monoclonal Antibody | Human,Mouse,Rat | ELISA,WB |
NOS3 Proteins
NOS3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015946MO CSB-EP015946MO CSB-BP015946MO CSB-MP015946MO CSB-EP015946MO-B |
Recombinant Mouse Nitric oxide synthase, endothelial (Nos3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015946SH CSB-EP015946SH CSB-BP015946SH CSB-MP015946SH CSB-EP015946SH-B |
Recombinant Sheep Nitric oxide synthase, endothelial (NOS3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Cavia porcellus (Guinea pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015946GU CSB-EP015946GU CSB-BP015946GU CSB-MP015946GU CSB-EP015946GU-B |
Recombinant Guinea pig Nitric oxide synthase, endothelial (NOS3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015946HU CSB-EP015946HU CSB-BP015946HU CSB-MP015946HU CSB-EP015946HU-B |
Recombinant Human Nitric oxide synthase, endothelial (NOS3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015946BO CSB-EP015946BO CSB-BP015946BO CSB-MP015946BO CSB-EP015946BO-B |
Recombinant Bovine Nitric oxide synthase, endothelial (NOS3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP637927PI CSB-EP637927PI CSB-BP637927PI CSB-MP637927PI CSB-EP637927PI-B |
Recombinant Pig Nitric oxide synthase, endothelial (NOS3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP733830RA CSB-EP733830RA CSB-BP733830RA CSB-MP733830RA CSB-EP733830RA-B |
Recombinant Rat Nitric oxide synthase, endothelial (Nos3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP165794r(A3) | Recombinant Rat Nitric oxide synthase, endothelial (Nos3), partial | E.coli |
NOS3 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP880009DO CSB-EP880009DO CSB-BP880009DO CSB-MP880009DO CSB-EP880009DO-B |
Recombinant Dog Nitric oxide synthase, endothelial (NOS3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 ELISA Kit
NOS3 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08322h | Human Endothelial nitric oxide synthase,eNOS ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 0.27 IU/mL |
NOS3 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08324m | Mouse Endothelial nitric oxide synthase,eNOS ELISA Kit | serum, plasma, tissue homogenates | 0.078 IU/mL |
NOS3 ELISA Kit for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08574p | Pig Endothelial nitric oxide synthase,eNOS ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 0.78 IU/mL |
NOS3 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08323r | Rat Endothelial nitric oxide synthase,eNOS/NOS3 ELISA Kit | serum, plasma, cell culture supernates, cell lysates | 3.9 μIU/mL |
