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NOD1

NOD1,即含核苷酸結合寡聚化結構域1,別名CARD4、NLRC1、CLR7.1等。它是一種在人體細胞中表達的蛋白質,屬于核苷酸結合寡聚化結構域(NOD)樣受體(NLR)家族。NOD1的作用機制是通過其N端的caspase募集結構域(CARD)、中心位置的核苷酸結合域(NBD)以及C端的10個串聯的富含亮氨酸重復序列(LRRs)來識別細菌肽聚糖,并引發炎癥反應,從而在天然免疫中發揮作用。NOD1還參與對病毒和寄生蟲感染的免疫反應。NOD1通過模式識別受體(PRR)的功能識別病原微生物并激活下游的炎癥和免疫應答。NOD1的突變與多種疾病相關,包括哮喘、炎癥性腸病、白塞病和結節病等。

熱銷產品

NOD1 Antibody (CSB-PA047815)

驗證數據

CSB-PA047815

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA047815(NOD1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA047815

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA047815(NOD1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

Human Nucleotide-binding oligomerization domain-containing protein 1(NOD1) ELISA kit (CSB-EL015914HU)

驗證數據

CSB-EL015914HU 標準曲線

貨號:CSB-EL015914HU

規格:96T/48T

靈敏度:3.9 pg/mL

檢測范圍:15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

NOD1 Antibodies

NOD1 for Homo sapiens (Human)

NOD1 Proteins

NOD1 Proteins for Mus musculus (Mouse)

NOD1 Proteins for Homo sapiens (Human)

NOD1 ELISA Kit

NOD1 ELISA Kit for Homo sapiens (Human)