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NFKBIA

NF-kappa-B inhibitor alpha is a protein in humans that is encoded by NFKBIA gene. Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

NFKBIA Antibodies

NFKBIA for Homo sapiens (Human)

NFKBIA Proteins

NFKBIA Proteins for Homo sapiens (Human)

NFKBIA Proteins for Rattus norvegicus (Rat)

NFKBIA Proteins for Gallus gallus (Chicken)