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MCM7

DNA replication licensing factor MCM7 is a protein in humans that is encoded by MCM7 gene. Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.

MCM7 Antibodies

MCM7 for Homo sapiens (Human)

MCM7 Proteins

MCM7 Proteins for Homo sapiens (Human)

MCM7 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

MCM7 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

MCM7 Proteins for Arabidopsis thaliana (Mouse-ear cress)

MCM7 Proteins for Bos taurus (Bovine)

MCM7 Proteins for Mus musculus (Mouse)

MCM7 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

MCM7 Proteins for Drosophila melanogaster (Fruit fly)



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