在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LEF1

Lymphoid enhancer-binding factor 1 is a protein in humans that is encoded by LEF1 gene. Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity). Isoform 3 lacks the CTNNB1 interaction domain and may be an antagonist for Wnt signaling. Isoform 5 transcriptionally activates the fibronectin promoter, binds to and represses transcription from the E-cadherin promoter in a CTNNB1-independent manner, and is involved in reducing cellular aggregation and increasing cell migration of pancreatic cancer cells. Isoform 1 transcriptionally activates MYC and CCND1 expression and enhances proliferation of pancreatic tumor cells.

LEF1 Antibodies

LEF1 for Homo sapiens (Human)

LEF1 Proteins

LEF1 Proteins for Mus musculus (Mouse)

LEF1 Proteins for Rattus norvegicus (Rat)

LEF1 Proteins for Homo sapiens (Human)



主站蜘蛛池模板: 国产精品美女久久久| 未满十八18禁止午夜免费网站| 日韩亚洲国产中文永久| 精品国产品香蕉在线| 久久天天躁狠狠躁夜夜网站| 亚洲欧洲日韩极速播放| 亚洲 欧洲 日韩 综合在线| 精品乱码一区二区三四五区| 中国女人做爰视频| 五月丁香六月综合av| 久久久久99人妻一区二区三区| 久久久774这里只有精品17| 国产av天堂亚洲国产av麻豆| 午夜精品久久久久久| 波多野结衣在线播放| 国产成人精品久久一区二区三区| 久久九九精品国产免费看小说| 精品久久久久久中文字幕人妻最新| 国产亚洲人成a在线v网站| 成年奭片免费观看视频天天看| 99久久久国产精品消防器材| 少妇被爽到高潮喷水久久欧美精品| 日韩精品毛片无码一区到三区| 色猫咪免费人成网站在线观看| 亚洲综合中文字幕无线码| 苍井空浴缸大战猛男120分钟| 丰满少妇被粗大的猛烈进出视频| 天天躁夜夜躁天干天干2020| 国产精品无码一区二区三区在 | 蜜桃网站入口可看18禁| 中文无码av在线亚洲电影| 久久综合噜噜激激的五月天| 欧美日韩国产一区二区三区不卡| 四虎国产精品永久在线无码| 国产成人无码精品久久久露脸| 亚洲 日韩 欧美 成人 在线观看| 中文人妻熟妇乱又伦精品| 色av专区无码影音先锋| 中文天堂国产最新| 香蕉欧美成人精品a∨在线观看| 免费无码久久成人网站入口|