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KIR2DL2

KIR2DL2,全稱為殺傷細胞免疫球蛋白樣受體2DL2,也被稱為NKAT6、p58.2、CD158b1。該蛋白是一種跨膜糖蛋白,屬于殺傷細胞免疫球蛋白樣受體(KIR)家族。KIR2DL2主要表達在自然殺傷(NK)細胞和部分T細胞上,通過識別HLA-C類分子來調節NK細胞的活化和抑制。它能夠抑制NK細胞的細胞毒性作用,從而防止正常細胞被錯誤地攻擊。KIR2DL2與多種疾病相關,包括癌癥、自身免疫性疾病等。在藥物研發方面,針對KIR2DL2的抗體已被開發出來,用于治療某些癌癥和自身免疫性疾病。

熱銷產品

KIR2DL2 Antibody (CSB-PA012353LA01HU)

驗證數據

CSB-PA012353LA01HU

Immunofluorescence staining of A549 cells with CSB-PA012353LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

KIR2DL2 Antibodies

KIR2DL2 for Homo sapiens (Human)

KIR2DL2 Proteins

KIR2DL2 Proteins for Homo sapiens (Human)