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IRF7

Interferon regulatory factor 7 is a protein in humans that is encoded by IRF7 gene. Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase.

IRF7 Antibodies

IRF7 for Homo sapiens (Human)

IRF7 Proteins

IRF7 Proteins for Mus musculus (Mouse)

IRF7 Proteins for Homo sapiens (Human)

IRF7 ELISA Kit

IRF7 ELISA Kit for Homo sapiens (Human)



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