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IGFBP7

IGFBP7,全稱為胰島素樣生長因子結合蛋白7,也被稱為IGFBP-7、TAF、MAC25、PSF等。該蛋白主要功能是調節胰島素樣生長因子(IGF)在體內的可用性,并影響IGF與其受體的結合。IGFBP7在多種組織中均有表達,尤其在骨骼肌中表達較高。研究發現,IGFBP7在骨骼肌的維持和修復中發揮重要作用,與肌肉萎縮等疾病相關。目前,IGFBP7已成為研究熱點,在藥物研發方面,針對其作用機制的研究有助于開發治療肌肉萎縮、癌癥等疾病的藥物。

熱銷產品

Recombinant Human Insulin-like growth factor-binding protein 7 (IGFBP7) (Active) (CSB-MP620956HUd9)

驗證數據

CSB-MP620956HUd9

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP620956HUd9

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CD93 (CSB-MP865099HU) at 2 μg/ml can bind Human IGFBP7. The EC50 is 3.405-5.456 ng/mL.

IGFBP7 Antibody (CSB-PA16259A0Rb)

驗證數據

CSB-PA16259A0Rb

Western Blot
Positive WB detected in: Rat kidney tissue
All lanes: IGFBP7 antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 30, 29 kDa
Observed band size: 30 kDa

IGFBP7 Antibodies

IGFBP7 for Homo sapiens (Human)

IGFBP7 Proteins

IGFBP7 Proteins for Homo sapiens (Human)

IGFBP7 ELISA Kit

IGFBP7 ELISA Kit for Homo sapiens (Human)