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IDE

IDE is a protein in humans that is encoded by IDE gene. Plays a role in the cellular breakdown of insulin, APP peptides, IAPP peptides, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Substrate binding induces important conformation changes, making it possible to bind and degrade larger substrates, such as insulin. Contributes to the regulation of peptide hormone signaling cascades and regulation of blood glucose homeostasis via its role in the degradation of insulin, glucagon and IAPP (By similarity). Plays a role in the degradation and clearance of APP-derived amyloidogenic peptides that are secreted by neurons and microglia (Probable). Involved in antigen processing. Produces both the N terminus and the C terminus of MAGEA3-derived antigenic peptide (EVDPIGHLY) that is presented to cytotoxic T lymphocytes by MHC class I.

IDE Antibodies

IDE for Homo sapiens (Human)

IDE for H

IDE Proteins

IDE Proteins for Homo sapiens (Human)

IDE Proteins for Rattus norvegicus (Rat)

IDE Proteins for Drosophila melanogaster (Fruit fly)

IDE Proteins for Mus musculus (Mouse)

IDE Proteins for Bos taurus (Bovine)



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