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HTR1B

5-hydroxytryptamine receptor 1B is a protein in humans that is encoded by HTR1B gene. G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.

HTR1B Antibodies

HTR1B for Homo sapiens (Human)

HTR1B Proteins

HTR1B Proteins for Sus scrofa (Pig)

HTR1B Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

HTR1B Proteins for Homo sapiens (Human)

HTR1B Proteins for Mus musculus (Mouse)

HTR1B Proteins for Oryctolagus cuniculus (Rabbit)

HTR1B Proteins for Cavia porcellus (Guinea pig)

HTR1B Proteins for Rattus norvegicus (Rat)

HTR1B Proteins for Didelphis marsupialis virginiana (North American opossum)

HTR1B Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

HTR1B Proteins for Spalax ehrenbergi (Middle East blind mole rat) (Nannospalax ehrenbergi)

HTR1B Proteins for Pan troglodytes (Chimpanzee)

HTR1B Proteins for Equus caballus (Horse)

HTR1B Proteins for Felis catus (Cat) (Felis silvestris catus)

HTR1B Proteins for Vulpes vulpes (Red fox)

HTR1B Proteins for Gorilla gorilla gorilla (Lowland gorilla)



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