HAP1
HAP1,全稱為亨廷頓蛋白相關蛋白1(Huntingtin-associated protein 1),是一種在神經系統中高表達的蛋白,與多種蛋白質相互作用。其常見別名為HAP1或huntingtin-interacting protein 1。HAP1參與囊泡運輸、基因轉錄和信號轉導等過程,對神經系統的多種活動至關重要。研究表明,HAP1在神經系統疾病中發揮重要作用,例如帕金森病和阿爾茨海默病。此外,HAP1在消化系統中也有表達,可能作為胰腺癌的診斷標志物。目前,針對HAP1的藥物研發正在積極進行中,旨在開發治療神經系統疾病和胰腺癌的新療法。
HAP1的研究進展為神經系統疾病的治療提供了新的思路和靶點。例如,一項研究發現,HAP1在神經細胞分化成熟中起關鍵作用,為治療神經退行性疾病提供了潛在靶點。另一項研究則發現,HAP1的表達在胰腺癌中下調,提示其可能作為診斷標志物。此外,科學家們正在探索HAP1與其他蛋白的相互作用,以尋找新的藥物靶點。這些研究進展為HAP1相關疾病的治療提供了新的希望。
熱銷產品
HAP1 Antibody (CSB-PA010129LA01HU)
驗證數據

Immunofluorescence staining of SH-SY5Y cells with CSB-PA010129LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
HAP1 Antibodies
HAP1 for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA010129LA01HU | HAP1 Antibody | Human | ELISA, IF |
CSB-PA010129LB01HU | HAP1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA010129LD01HU | HAP1 Antibody, Biotin conjugated | Human | ELISA |
HAP1 Proteins
HAP1 Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP010129HU CSB-EP010129HU CSB-BP010129HU CSB-MP010129HU CSB-EP010129HU-B |
Recombinant Human Huntingtin-associated protein 1 (HAP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |