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GTF2I

General transcription factor II-I is a protein in humans that is encoded by GTF2I gene. Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.

GTF2I Antibodies

GTF2I for Homo sapiens (Human)

GTF2I Proteins

GTF2I Proteins for Homo sapiens (Human)

GTF2I Proteins for Bos taurus (Bovine)

GTF2I Proteins for Rattus norvegicus (Rat)

GTF2I Proteins for Mus musculus (Mouse)



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