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GPBAR1

GPBAR1,即G蛋白偶聯膽汁酸受體1,別名TGR5、GPCR19、hGPCR19、M-BAR、BG37等。它來源于人體細胞內的基因表達,是G蛋白偶聯受體家族的一員。GPBAR1的作用機制主要通過識別并結合膽汁酸,激活下游信號通路,從而參與代謝調控、炎癥反應和能量平衡等生理過程。在生物學意義上,GPBAR1對于維持機體內環境穩定、預防代謝性疾病和炎癥性疾病具有重要意義,同時也是藥物研發的重要靶點之一。

熱銷產品

Recombinant Human?G-protein?coupled?bile?acid?receptor?1 (GPBAR1) (CSB-CF819471HU)

驗證數據

CSB-CF819471HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

GPBAR1 Antibody (CSB-PA819471LA01HU)

驗證數據

CSB-PA819471LA01HU

Western Blot
Positive WB detected in: Mouse kidney tissue
All lanes: GPBAR1 antibody at 6μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 36 kDa
Observed band size: 36 kDa

CSB-PA819471LA01HU

IHC image of CSB-PA819471LA01HU diluted at 1:300 and staining in paraffin-embedded human bladder cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA819471LA01HU

Immunofluorescence staining of 293 cells with CSB-PA819471LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Human G protein-coupled bile acid receptor 1(GPBAR1) ELISA Kit (CSB-E13937h)

驗證數據

CSB-E13937h 標準曲線

貨號:CSB-E13937h

規格:96T/48T

靈敏度:0.039 ng/mL

檢測范圍:0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

GPBAR1 Antibodies

GPBAR1 for Homo sapiens (Human)

GPBAR1 Proteins

GPBAR1 Proteins for Rattus norvegicus (Rat)

GPBAR1 Proteins for Oryctolagus cuniculus (Rabbit)

GPBAR1 Proteins for Bos taurus (Bovine)

GPBAR1 Proteins for Mus musculus (Mouse)

GPBAR1 Proteins for Homo sapiens (Human)

GPBAR1 ELISA Kit

GPBAR1 ELISA Kit for Homo sapiens (Human)



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