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ELF3

Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).

ELF3 Antibodies

ELF3 for Homo sapiens (Human)

ELF3 Proteins

ELF3 Proteins for Homo sapiens (Human)

ELF3 Proteins for Arabidopsis thaliana (Mouse-ear cress)

ELF3 Proteins for Mus musculus (Mouse)

ELF3 Proteins for Rattus norvegicus (Rat)



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