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DLL4

DLL4,全稱為Delta-like protein 4。它在Notch信號通路中扮演重要角色,作為Notch配體激活NOTCH1和NOTCH4,參與細胞通信和血管生成調控。DLL4蛋白與多種疾病相關,如上皮性卵巢癌等。在藥物研發方面,DLL4蛋白已成為抗腫瘤治療的新靶點,相關雙抗藥物如VEGF/DLL4雙抗在臨床試驗中取得顯著進展,有望成為膽道癌二線治療的新標準。

熱銷產品

Recombinant Human Delta-like protein 4 (DLL4),partial (Active) (CSB-MP878862HU)

驗證數據

CSB-MP878862HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP878862HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human DLL4 at 2 μg/ml can bind Anti-DLL4 recombinant antibody (CSB-RA878862MA1HU). The EC50 is 2.322-2.607 ng/mL.

DLL4 (Navicixizumab) Recombinant Monoclonal Antibody (CSB-RA878862MA1HU)

驗證數據

CSB-RA878862MA1HU

The Binding Activity of Human DLL4 with Anti-DLL4 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DLL4 (CSB-MP878862HU) at 2 μg/mL can bind Anti-DLL4 recombinant antibody . The EC50 is 2.322-2.607 ng/mL.

DLL4 Antibodies

DLL4 for Homo sapiens (Human)

DLL4 Proteins

DLL4 Proteins for Xenopus laevis (African clawed frog)

DLL4 Proteins for Mus musculus (Mouse)

DLL4 Proteins for Homo sapiens (Human)

DLL4 ELISA Kit

DLL4 ELISA Kit for Homo sapiens (Human)

DLL4 ELISA Kit for Mus musculus (Mouse)