DHCR7
DHCR7,全稱為7-脫氫膽固醇還原酶,是一種重要的酶,負責將7-脫氫膽固醇轉化為膽固醇。該蛋白有多種別名,如7-DHC還原酶、DHCR7抗體等。它在細胞膜中發揮關鍵作用,參與膽固醇的代謝。DHCR7的異常可能導致Smith-Lemli-Opitz綜合征(SLOS),這是一種影響膽固醇代謝的遺傳疾病,患者可能出現認知障礙、面部畸形等癥狀。近年來,研究人員發現DHCR7在抗病毒感染中也扮演重要角色,因此,針對DHCR7的藥物研發成為研究熱點。目前,已有一些研究探索了DHCR7抑制劑在治療病毒感染中的應用潛力。
熱銷產品
DHCR7 Antibody (CSB-PA006844LA01HU)
驗證數據

Western Blot
Positive WB detected in: HepG2 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate
All lanes: DHCR7 antibody at 2.4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa

IHC image of CSB-PA006844LA01HU diluted at 1:600 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
DHCR7 Antibodies
DHCR7 for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA900410 | DHCR7 Antibody | Human,Mouse | ELISA,IHC |
CSB-PA110763 | DHCR7 Antibody | Human,Mouse | ELISA,IHC |
CSB-PA006844LA01HU | DHCR7 Antibody | Human | ELISA, WB, IHC |
CSB-PA006844LD01HU | DHCR7 Antibody, Biotin conjugated | Human | ELISA |
DHCR7 Proteins
DHCR7 Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP006844HU1 CSB-EP006844HU1 CSB-BP006844HU1 CSB-MP006844HU1 CSB-EP006844HU1-B |
Recombinant Human 7-dehydrocholesterol reductase (DHCR7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF006844HU | Recombinant Human 7-dehydrocholesterol reductase (DHCR7) | in vitro E.coli expression system |