CPN2
CAPN2(Calpain-2)是一種半胱氨酸蛋白酶,全稱為鈣蛋白酶-2,別名為Mu-calpain或Capn2。該蛋白參與細胞信號調控、蛋白質降解和細胞凋亡等過程,在神經系統和肌肉組織中發揮重要作用。CAPN2通過水解靶蛋白,影響細胞功能,與多種生理病理過程相關。研究表明,CAPN2異常表達或活性失衡與神經退行性疾病(如阿爾茨海默病)、癌癥和自身免疫性疾病等有關。在藥物研發方面,針對CAPN2的抑制劑和激活劑正被探索用于治療相關疾病。例如,BTM-3566是一種靶向OMA1和CAPN2的抗癌新藥,已在臨床試驗中展示潛力。此外,多靶點藥物和多特異性抗體等創新療法也關注CAPN2的作用,為疾病治療提供新思路。隨著研究的深入,CAPN2相關藥物有望為神經退行性疾病和癌癥患者帶來更多臨床獲益。
熱銷產品
Recombinant Human Carboxypeptidase N subunit 2 (CPN2) (CSB-EP005899HU)
驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Carboxypeptidase N subunit 2(CPN2) ELISA kit (CSB-EL005899HU)
驗證數據

貨號:CSB-EL005899HU
規格:96T/48T
靈敏度:0.039 ng/mL
檢測范圍:0.156 ng/mL-10 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CPN2 Antibodies
CPN2 for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA276934 | CPN2 Antibody | Human | ELISA,WB |
CSB-PA007245 | CPN2 Antibody | Human | WB, ELISA |
CPN2 Proteins
CPN2 Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP005899HU CSB-BP005899HU CSB-EP005899HU-B |
Recombinant Human Carboxypeptidase N subunit 2 (CPN2) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
CSB-EP005899HU | Recombinant Human Carboxypeptidase N subunit 2 (CPN2) | E.coli |
CSB-MP005899HU | Recombinant Human Carboxypeptidase N subunit 2 (CPN2) | Mammalian cell |
CPN2 ELISA Kit
CPN2 ELISA Kit for Homo sapiens (Human)
產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-EL005899HU | Human Carboxypeptidase N subunit 2(CPN2) ELISA kit | serum, plasma, tissue homogenates | 0.039 ng/mL |