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  4. Recombinant Deinococcus radiodurans DNA protection during starvation protein 1 (dps1)

Recombinant Deinococcus radiodurans DNA protection during starvation protein 1 (dps1)

  • 中文名稱：
    放射性紅球菌dps1重組蛋白
  • 貨號：
    CSB-YP865732DJA
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    放射性紅球菌dps1重組蛋白
  • 貨號：
    CSB-EP865732DJA
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    放射性紅球菌dps1重組蛋白
  • 貨號：
    CSB-EP865732DJA-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    放射性紅球菌dps1重組蛋白
  • 貨號：
    CSB-BP865732DJA
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    放射性紅球菌dps1重組蛋白
  • 貨號：
    CSB-MP865732DJA
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    dps1
  • Uniprot No.：
  • 別名：
    dps1; dps-1; DR_2263DNA protection during starvation protein 1; EC 1.16.-.-
  • 種屬：
    Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-207
  • 氨基酸序列
    MTKKSTKSEA ASKTKKSGVP ETGAQGVRAG GADHADAAHL GTVNNALVNH HYLEEKEFQT VAETLQRNLA TTISLYLKFK KYHWDIRGRF FRDLHLAYDE FIAEIFPSID EQAERLVALG GSPLAAPADL ARYSTVQVPQ ETVRDARTQV ADLVQDLSRV GKGYRDDSQA CDEANDPVTA DMYNGYAATI DKIRWMLQAI MDDERLD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Both oligomeric forms of dps exhibit ferroxidase activity and DNA binding. Dodecameric dps is capable of Fe(2+) oxidation/mineralization. Only dimeric dps affords efficient DNA protection against hydroxyl radical-mediated cleavage.
  • 基因功能參考文獻：
    1. Dps-1 may function in DNA metabolism. PMID: 22857940
    2. Data describe the cloning and characterization of a DNA protection during starvation (Dps) homolog from Deinococcus radiodurans and show that DNA binding does not require its assembly into a dodecamer. PMID: 15755446
    3. It was found that DR2263 has an extended N-terminal extension, in both structures presented here, a novel metal binding site was identified in this N-terminal extension and was assigned to bound zinc.[DR2263 protein] PMID: 16855817
  • 亞細胞定位：
    Cytoplasm, nucleoid.
  • 蛋白家族：
    Dps family
  • 數據庫鏈接：

    KEGG: dra:DR_2263

    STRING: 243230.DR_2263



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