在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Inducible T-cell costimulator (Icos), partial

  • 中文名稱:
    大鼠Icos重組蛋白
  • 貨號:
    CSB-EP889939RA
  • 規格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Icos; Ailim; Inducible T-cell costimulator; Activation-inducible lymphocyte immunomediatory molecule; CD antigen CD278
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Extracellular Domain
  • 來源:
    E.coli
  • 分子量:
    18.1kDa
  • 表達區域:
    21-145aa
  • 氨基酸序列
    ELNDLANHRMFSFHDGGVQISCNYPETVQQLKMQLFKDREVLCDLTKTKGSGNTVSIKNPMSCPYQLSNNSVSFFLDNADSSQGSYFLCSLSIFDPPPFQEKNLSGGYLLIYESQLCCQLKLWLP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
  • 基因功能參考文獻:
    1. ICOS-targeted siRNA can effectively silence gene expression of ICOS, and provided satisfactory treatment efficacy for myocardial cell hypertrophy after infarction. PMID: 27323062
    2. ICOS siRNA can protect brain tissues from ischemia injuries after cerebral infarction, improve limb movement and coordination, lower the mortality rate of rats, and inhibit T cell-induced cytokines PMID: 26436531
    3. our data highlight a key role for ICOS signaling in the generation of imbalanced production of IL-10 and IL-17 by Treg cells in a rat model of spondyloarthritis. PMID: 24909668
  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Strongly expressed in the spleen and lung. Lower expression seen in liver, kidney and testis.
  • 數據庫鏈接:


主站蜘蛛池模板: 国产乱人伦app精品久久| 国产欧美亚洲日韩图片| 亚洲乱码一区二区三区在线观看 | 夜夜躁日日躁狠狠久久av| 激情欧美日韩一区二区| 在线播放无码后入内射少妇| 果冻传媒2021精品一区| 国产午夜理论不卡在线观看| 色偷偷色噜噜狠狠网站久久| 极品少妇hdxx麻豆hdxx| 亚洲国产av天码精品果冻传媒| 蜜桃av蜜臀av色欲av麻| 亚洲aⅴ男人的天堂在线观看| 亚洲精品久久久蜜桃| 办公丝袜av一区二区三区| 国产精品无码a∨麻豆| 亚洲欧洲精品成人久久曰| 亚洲成在人线av无码| 亚洲精品无码成人aaa片 | 亚洲学生妹高清av| 国产精品兄妹在线观看麻豆 | 99在线精品国自产拍| 国产白嫩美女在线观看| 亚洲中文无码a∨在线观看| 无码国模大尺度视频在线观看| 国产精品二区一区二区aⅴ污介绍| 在线观看免费人成视频色9| 火箭视频在线观看精品| 欧美日韩视频在线第一区 | 久久久精品中文字幕乱码18| 浪潮av激情高潮国产精品| 国产精品爆乳在线播放第一人称| 欧美 日产 国产在线观看| 蜜臀avwww国产天堂| 欧美俄罗斯乱妇| 亚洲乱码中文字幕久久孕妇黑人| 天干天干夜啦天干天干国产| 97se色综合一区二区二区| 卡一卡二卡三免费视频| 国产精品自在自线视频| 国产卡一卡二卡三精品|