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  4. TCP10L Antibody, FITC conjugated

TCP10L Antibody, FITC conjugated

  • 中文名稱：
    TCP10L兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA823465LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TCP10L Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TCP10L
  • 別名：
    TCP10L antibody; PRED77 antibody; T-complex protein 10A homolog 1 antibody; T-complex protein 10A-1 antibody; TCP10A-1 antibody; TCP10-like antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human T-complex protein 10A homolog 2 protein (1-215AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be involved in transcriptional regulation. Has in vitro transcription inhibition activity. Acts as a tumor suppressor in hepatocellular carcinoma (HCC) cells.
  • 基因功能參考文獻：
    1. TCP10L stabilizes MAD1 protein level through direct interaction, and they cooperatively regulate cell cycle progression. PMID: 26698869
    2. Overexpression of TCP10L in hepatocellular carcinoma cells suppressed colony formation, inhibited cell cycle progression through G0/G1 phase, and attenuated cell growth in vivo. PMID: 24565846
    3. The result revealed that TCP10L expressed specifically in the human liver and testis PMID: 14586771
    4. Data suggest that the biological function of the interaction between T-complex protein 10-like and MAD4 may be to maintain the differentiation state in liver cells. PMID: 15469726
    5. The specific expression pattern of TCP10L and interaction with DAPK-3 implies that TCP10L might play crucially important roles in spermatogenesis through its interaction with DAPK-3. PMID: 15910542

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    TCP10 family
  • 組織特異性：
    Expressed in liver and testis. Expressed in the seminiferous tubules (at protein level).
  • 數據庫鏈接：

    HGNC: 11657

    OMIM: 608365

    KEGG: hsa:140290

    STRING: 9606.ENSP00000300258

    UniGene: Hs.728804



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