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  4. PLEK2 Antibody

PLEK2 Antibody

  • 中文名稱：
    PLEK2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA018153GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    PLEK2
  • 別名：
    Pleckstrin 2 (mouse) homolog antibody; Pleckstrin 2 antibody; Pleckstrin-2 antibody; PLEK 2 antibody; PLEK2 antibody; PLEK2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PLEK2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.
  • 基因功能參考文獻(xiàn)：
    1. expression of PLEK2, the strongest gene to classify melanoma patients, in CD45(-) subsets illustrates the importance of analyzing whole blood cells for biomarker studies PMID: 21698244
    2. Pleckstrin 2 was cloned; its mRNA is widely expressed in a variety of cell lines. PMID: 15865208
    3. pleckstrin-2 uses its modular domains to bind to membrane-associated phosphatidylinositols generated by PI3K, whereby it coordinates with the actin cytoskeleton in lymphocyte spreading and immune synapse formation. PMID: 17008542
    4. These results suggest that PLEK2 is involved in actin rearrangement in a PI 3-kinase dependent manner. PMID: 17658464
  • 亞細(xì)胞定位：
    Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19238

    OMIM: 608007

    KEGG: hsa:26499

    STRING: 9606.ENSP00000216446

    UniGene: Hs.170473



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