在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D)

  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-YP839163PI
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-EP839163PI
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-EP839163PI-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-BP839163PI
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-MP839163PI
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CAMK2D; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II subunit delta; CaMK-II subunit delta; EC 2.7.11.17
  • 種屬:
    Sus scrofa (Pig)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-499
  • 氨基酸序列
    ASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPS CIPNGKENFS GSTSLWQNI
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopathy and heart failure. Contributes to cardiac decompensation and heart failure by regulating SR Ca(2+) release via direct phosphorylation of RYR2 Ca(2+) channel on 'Ser-2808'. In the nucleus, phosphorylates the MEF2 repressor HDAC4, promoting its nuclear export and binding to 14-3-3 protein, and expression of MEF2 and genes involved in the hypertrophic program. Is essential for left ventricular remodeling responses to myocardial infarction. In pathological myocardial remodeling acts downstream of the beta adrenergic receptor signaling cascade to regulate key proteins involved in ECC. Regulates Ca(2+) influx to myocytes by binding and phosphorylating the L-type Ca(2+) channel subunit beta-2 CACNB2. In addition to Ca(2+) channels, can target and regulate the cardiac sarcolemmal Na(+) channel Nav1.5/SCN5A and the K+ channel Kv4.3/KCND3, which contribute to arrhythmogenesis in heart failure. Phosphorylates phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2, contributing to the enhancement of SR Ca(2+) uptake that may be important in frequency-dependent acceleration of relaxation (FDAR) and maintenance of contractile function during acidosis. May participate in the modulation of skeletal muscle function in response to exercise, by regulating SR Ca(2+) transport through phosphorylation of PLN/PLB and triadin, a ryanodine receptor-coupling factor.
  • 亞細胞定位:
    Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 精品久久久无码人妻字幂| 欧洲精品一卡2卡三卡4卡影视| 国产精品三级av及在线观看| 亚洲另类欧美综合久久图片区| 日本中文字幕乱码免费| 精品无人区无码乱码毛片国产| 国产精品国产三级国产a| 人妻少妇精品视频无码专区| 国产午夜精品一二区理论影院| 2020国产在线拍揄自揄视频 | 亚洲 欧美 激情 小说 另类| 国产精品久久777777| 丝袜高跟麻麻浓精受孕人妻| 国产成人国拍亚洲精品| 亚洲精品久久久久国产剧8| av小次郎收藏| 亚洲国产成人精品无码区99| 亚洲国产欧美在线人成大黄瓜 | 播放男人添女人下边视频| 人妻少妇乱子伦无码专区| 99久久国产亚洲高清观看| 成人奭片免费观看| 国产乱子夫妻xx黑人xyx真爽| aaaaa少妇高潮大片| 97久久婷婷五月综合色d啪蜜芽| 亚洲国产精品无码专区影院| 成人婷婷网色偷偷亚洲男人的天堂| 97人妻人人做人碰人人爽| 日韩插啊免费视频在线观看| 中文字幕v亚洲日本在线电影 | a欧美爰片久久毛片a片| 国产午夜精品一区二区三区不卡 | 性做久久久久久久久| 人妻人人澡人人添人人爽| 伊人色综合网一区二区三区| 免费无码在线播放av| 性色av无码不卡中文字幕| 狠狠色婷婷久久综合频道日韩| 国产在不卡免费一区二区三| 人人爽人人爽人人片av亚洲| 国产亚洲精品久久久久久青梅|