在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MLX Antibody

MLX Antibody

  • 中文名稱：
    MLX兔多克隆抗體
  • 貨號：
    CSB-PA227729
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from LOVO cells, using Mlx antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MLX Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MLX
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human Mlx.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
  • 基因功能參考文獻：
    1. MYC is part of a network of bHLHLZ proteins centered on the MYC heterodimeric partner MAX and its counterpart, the MAX-like protein MLX. PMID: 24857747
    2. Knockdown of MondoA, or its dimerization partner Mlx, blocks Myc-induced reprogramming of multiple metabolic pathways, resulting in apoptosis PMID: 25640402
    3. Data show that for both MondoA and Mlx, the C-terminal domain CRM-1 has cytoplasmic localization activity that is required by the protein monomers to accumulate in the cytoplasm. PMID: 12446771
    4. Mlx is an obligatory partner of ChREBP in regulating lipogenic enzyme genes in liver. PMID: 15664996
    5. Endogenous MondoA and Mlx associate with mitochondria in primary skeletal muscle. PMID: 16782875
    6. These studies suggest a key role for MondoA:Mlx complexes in the adaptive transcriptional response to changes in extracellular glucose concentration and peripheral glucose uptake. PMID: 18458340

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform Alpha]: Cytoplasm.; [Isoform Beta]: Cytoplasm.; [Isoform Gamma]: Nucleus.
  • 組織特異性：
    Expressed in all tissues tested, including spleen, thymus, prostate, ovary, intestine, colon, peripheral blood leukocyte, heart, liver, skeletal muscle and kidney. Lower levels of expression in testis, brain, placenta and lung.
  • 數據庫鏈接：

    HGNC: 11645

    OMIM: 602976

    KEGG: hsa:6945

    STRING: 9606.ENSP00000246912

    UniGene: Hs.383019



主站蜘蛛池模板： 女人被狂爆到高潮免费视频| 天干天干天啪啪夜爽爽av| 人妻另类 专区 欧美 制服| 韩国无码av片在线观看| 国内高清a自拍视频| 国产欧美va欧美va香蕉在线| 老太婆性杂交视频| 国产亚洲产品影视在线产品| 丰满少妇人妻hd高清大乳在线| 国产精品久久久久aaaa| av午夜久久蜜桃传媒软件| 色噜噜亚洲男人的天堂| 大香网伊人久久综合网2018| 久久综合久色欧美综合狠狠| 凹凸精品熟女在线观看| 国产激情无码一区二区app| 亚洲精品1卡2卡三卡23卡| 老妇女性较大毛片| 无码av免费永久免费永久专区| 欧美性猛交xxxxx按摩欧美| 国产成人精品一区二区三区无码| 国产剧情国产精品一区| 午夜精品久久久久9999| 欧美黑人xxxx性高清版| 隔壁邻居是巨爆乳寡妇| 国产黄网永久免费视频大全| 四虎永久在线精品8848a| 日本爽爽爽爽爽爽在线观看免 | 国产吃奶在线观看| 桃花色综合影院| 日日噜噜夜夜狠狠久久无码区 | 国内大量揄拍人妻在线视频| 羞涩的丰满人妻40p| 亚洲永久无码7777kkk| 无码人妻丰满熟妇精品区| 亚洲欧美日韩中文二区| 天天狠天天透天天伊人| 国模欢欢炮交啪啪150| 久久久国产精品va麻豆| 又粗又大又黄又爽的免费视频| 国产无遮挡又黄又爽又色|