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mcr1 Antibody, FITC conjugated

Rare Species
  • 中文名稱:
    mcr1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA745804FC01ENL
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Mouse anti-Escherichia coli mcr1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    mcr1
  • 別名:
    mcr1; mcr-1; APZ14_31440; Probable phosphatidylethanolamine transferase Mcr-1; Polymyxin resistance protein MCR-1
  • 宿主:
    Mouse
  • 反應種屬:
    Escherichia coli
  • 免疫原:
    Recombinant Escherichia coli Probable phosphatidylethanolamine transferase Mcr-1 protein (1-541AA)
  • 免疫原種屬:
    Escherichia coli
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Probably catalyzes the addition of a phosphoethanolamine moiety to lipid A. Phosphoethanolamine modification of lipid A gives polymyxin resistance.; Confers resistance to polymyxin-type antibiotics; expression of the Mcr-1 protein in E.coli increases colistin and polymyxin B minimal inhibitory concentration (MIC) from 0.5 mg/ml to 2.0 mg/ml. The pHNSHP45 plasmid can transfer efficiently (0.1 to 0.001) to other E.coli strains by conjugation and increases polymxin MIC by 8- to 16-fold; it may not require selective pressure to be maintained in the cell. When transformed into K.pneumoniae or P.aeruginosa it also increases polymxin MIC 8- to 16-fold. In a murine (BALB/c mice) thigh infection study using an mcr1-encoding plasmid isolated from a human patient, the plasmid confers in vivo protection against colistin.
  • 亞細胞定位:
    Cell inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Phosphoethanolamine transferase family


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