在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Inhibitor of growth protein 1 (Ing1)

Recombinant Mouse Inhibitor of growth protein 1 (Ing1)

  • 中文名稱：
    小鼠Ing1重組蛋白
  • 貨號：
    CSB-YP865583MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ing1重組蛋白
  • 貨號：
    CSB-EP865583MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ing1重組蛋白
  • 貨號：
    CSB-EP865583MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ing1重組蛋白
  • 貨號：
    CSB-BP865583MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ing1重組蛋白
  • 貨號：
    CSB-MP865583MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Ing1
  • Uniprot No.：
  • 別名：
    Ing1; Inhibitor of growth protein 1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-279
  • 氨基酸序列
    MLSPANGEQI HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDDYYEKFKR ETDGTQKRRV LHCIQRALIR SQELGDEKIQ IVSQMVELVE NRSRQVDSHV ELFEAHQDIS DGTGGSGKAG QDKSKSEAIT QADKPNNKRS RRQRNNENRE NASNNHDHDD ITSGTPKEKK AKTSKKKKRS KAKAEREASP ADLPIDPNEP TYCLCNQVSY GEMIGCDNDE CPIEWFHFSC VGLNHKPKGK WYCPKCRGES EKTMDKALEK SKKERAYNR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Isoform 1 inhibits p53-dependent transcriptional activation and may function as an oncoprotein. Isoform 2 acts as a negative growth regulator by cooperating with p53 in transcriptional activation of p53-responsive genes and may act as a tumor suppressor.
  • 基因功能參考文獻：
    1. Taken together, our findings provide evidence for a novel crosstalk and a crossregulation between ING1 and ING2 in regulating androgen receptor-mediated transactivation and suggest that ING2 acts as a novel corepressor that inhibits AR signaling, prostate cancer cell growth, and migration. PMID: 27305909
    2. ING1b is an important regulator of osteoblast differentiation and suppresses PPAR-beta/delta. PMID: 26849833
    3. Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1. PMID: 24655373
    4. Study reveals a novel connection between ING1 and a regulator of microRNA biogenesis and identifies new links between tumor suppressor proteins and the microRNA machinery. PMID: 20179197
    5. Identification of the p33(ING1)-regulated genes that include cyclin B1 and proto-oncogene DEK by using cDNA microarray in a mouse mammary epithelial cell line NMuMG PMID: 11956069
    6. Characterization of nuclear localization signal in mouse ING1 homolog protein. PMID: 12054579
    7. p33ING1 expression induces features of cellular senescence through two silencing domains and interaction with Ras PMID: 15601862
    8. the suggested role of ing1 as a candidate tumor suppressor gene involved in control of DNA damage response. PMID: 16170338
    9. p37(Ing1) can negatively regulate cell growth and apoptosis in a p53-independent manner. PMID: 17332334
    10. Analysis of marker gene expression in p37(Ing1b)/p53 null tumors indicates that the double-null mice develop both nongerminal center and germinal center B-cell-like DLBL. PMID: 18974112

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    ING family
  • 組織特異性：
    In the adult, widely expressed with highest levels in thymus and testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 99精品久久99久久久久| 日本丰满大乳乳液| 亚洲人成网站18禁止大| 日韩不卡1卡2卡三卡2021精品推荐 | 蜜臀av免费一区二区三区| 欧美疯狂做受xxxx高潮| 精品久久久久成人码免费动漫| 国产精品无码一区二区三区 | 无码人妻一区二区三区四区av| 国产精品美女久久久久av爽| 久久久久久综合网天天| 啦啦啦中文在线观看日本| 午夜福利一区二区三区高清视频| 国产午夜不卡片免费视频| 色无码av在线播放| 亚洲国产一区二区三区在线观看| 人妻丰满熟妇av无码区不卡| 老师黑色丝袜被躁翻了av| 色偷偷www.8888在线观看| 亚洲日韩中文字幕在线播放| 国产成人精品无码免费看夜聊软件| 欧美丰满少妇xxxx性| 国产精品69人妻无码久久| 亚洲欧美综合精品二区| 国产精品va无码免费| 无码日韩精品一区二区免费| 国产xxxx视频在线| 午夜国产成人片在线播放| 亚洲国产精久久久久久久| 国产精品久久久久久久久久久不卡| 无码高潮又爽又黄a片软件| 国产亚洲一卡2卡3卡4卡网站| av无码午夜福利一区二区三区| 国产精品亚洲二区在线观看| 香蕉av福利精品导航| 在线播放免费人成毛片乱码| 久久久久人妻一区精品果冻| 久久久久黑人强伦姧人妻| 国产va免费精品高清在线| 久久国产偷任你爽任你| 日韩欧群交p片内射中文|