在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Ceramide synthase 1 (Cers1)

  • 中文名稱:
    Recombinant Mouse Ceramide synthase 1(Cers1)
  • 貨號:
    CSB-CF012761MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    Cers1
  • Uniprot No.:
  • 別名:
    Cers1; Lass1; Uog-1; Uog1; Ceramide synthase 1; CerS1; Longevity assurance gene 1 protein homolog 1; Protein UOG-1; Sphingoid base N-stearoyltransferase CERS1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-350
  • 氨基酸序列
    MAAAAATPRLEAPEPMPSYAQMLQRSWASALAAAQGCGDCGWGLARRGLAEHAHLAAPEL LLAVLCALGWTALRWAATTHIFRPLAKRCRLQPRDAARLPESAWKLLFYLACWSYCAYLL LGTSYPFFHDPPSVFYDWRSGMAVPWDIAVAYLLQGSFYCHSIYATVYMDSWRKDSVVML VHHVVTLLLIASSYAFRYHNVGLLVFFLHDVSDVQLEFTKLNIYFKARGGAYHRLHGLVA NLGCLSFCFCWFWFRLYWFPLKVLYATCHCSLQSVPDIPYYFFFNILLLLLMVMNIYWFL YIVAFAAKVLTGQMRELEDLREYDTLEAQTAKPCKAEKPLRNGLVKDKLF
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward stearoyl-CoA (octadecanoyl-CoA; C18:0-CoA). N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. Plays a predominant role in skeletal muscle in regulating C18 ceramide and dihydroceramide levels with an impact on whole-body glucose metabolism and insulin sensitivity. Protects from diet-induced obesity by suppressing the uptake of glucose in multiple organs in a FGF21-dependent way. Generates C18 ceramides in the brain, playing a critical role in cerebellar development and Purkinje cell function. In response to cellular stress mediates mitophagy, a known defense mechanism against cell transformation and aging. Upon mitochondria fission, generates C18 ceramides that anchor lipidated MAP1LC3B/LC3B-II autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria.
  • 基因功能參考文獻:
    1. The strong association of LCB levels with neuronal survival both in vivo and in vitro suggests high-level accumulation of LCBs is a possible underlying cause of the CerS1 deficiency-induced neuronal death. PMID: 27162368
    2. an essential function of CerS1-derived ceramide in the regulation of cerebellar development and neurodevelopmentally regulated behavior. PMID: 23074226
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 組織特異性:
    Expressed in brain, skeletal muscle, heart and perigonadal white adipose tissue.
  • 數據庫鏈接:


主站蜘蛛池模板: 天堂а在线中文在线新版| 解开人妻的裙子猛烈进入| 日韩精品久久无码人妻中文字幕| 久久综合九色综合久99| 国产av一区二区三区日韩| 亚洲人成中文字幕在线观看| 夜夜影院未满十八勿进| 五月婷婷开心中文字幕| 无码中文字幕日韩专区| 麻批好紧日起要舒服死了| 黑人巨茎大战欧美白妇免费| 麻豆精品一卡二卡三卡| 国产欧美另类精品久久久| 国产无遮挡色视频免费观看性色| 亚洲国产成人精品无码区蜜柚| 国产偷国产偷亚洲清高孕妇| 亚洲妇女自偷自偷图片| 狠狠色噜噜狠狠狠777米奇888| 动漫精品视频一区二区三区| 青草青草视频2免费观看| 亚洲色欲色欱www在线| 少妇久久久久久久久久| 荫蒂添的好舒服视频囗交| 亚洲午夜私人影院在线观看| 久久久久青草线蕉亚洲麻豆| 久久久精品2019免费观看| 中文字幕无码热在线视频| 国产v片在线播放免费无遮挡| 亚洲精品久久久久一区二区三区 | 国语国产精精品国产国语清晰对话 | 精品无人码麻豆乱码1区2区| 国产亚洲精品精品国产亚洲综合| 国产午夜精品一区理论片飘花 | 无码国产精品一区二区免费式直播| 一个人看的日本hd免费| 性大毛片视频| 亚洲成色在线综合网站| 国产精品无码av在线一区| 97se亚洲国产综合自在线| 青青热久免费精品视频| 精品人妻无码一区二区三区蜜桃一|