在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Androgen-dependent TFPI-regulating protein (ADTRP)

  • 中文名稱:
    Recombinant Human Androgen-dependent TFPI-regulating protein(ADTRP)
  • 貨號:
    CSB-CF846640HUb3
  • 規(guī)格:
    ¥9720
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    ADTRP
  • Uniprot No.:
  • 別名:
    ADTRP; C6orf105; Androgen-dependent TFPI-regulating protein; Fatty acid esters of hydroxy fatty acids hydrolase ADTRP; FAHFA hydrolase ADTRP
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    in vitro E.coli expression system
  • 分子量:
    46.8kDa
  • 表達區(qū)域:
    1-230aa
  • 氨基酸序列
    MTKTSTCIYHFLVLSWYTFLNYYISQEGKDEVKPKILANGARWKYMTLLNLLLQTIFYGVTCLDDVLKRTKGGKDIKFLTAFRDLLFTTLAFPVSTFVFLAFWILFLYNRDLIYPKVLDTVIPVWLNHAMHTFIFPITLAEVVLRPHSYPSKKTGLTLLAAASIAYISRILWLYFETGTWVYPVFAKLSLLGLAAFFSLSYVFIASIYLLGEKLNHWKWGDMRQPRKKRK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids. Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids. Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro).
  • 基因功能參考文獻:
    1. These data suggest that one molecular mechanism by which androgen confers protection against coronary artery disease is stimulation of ADTRP expression. PMID: 28645652
    2. ADTRP positively regulates PIK3R3 expression, which leads to activation of AKT and up-regulation of MIA3/TANGO1, thereby regulating endothelial cell functions directly relevant to atherosclerosis. PMID: 28341552
    3. ADTRP increases the number of S phase cells during cell cycle. PMID: 27235449
    4. These results indicate that AIG1 and ADTRP are founding members of an evolutionarily conserved class of transmembrane threonine hydrolases involved in bioactive lipid metabolism. PMID: 27018888
    5. association of ADTRP with the pathogenesis of early-onset CAD PMID: 26375920
    6. SNP rs6903956 associated with asymptomatic hyperuricemia susceptibility in Han Chinese PMID: 25928384
    7. Activation of PPARG increases the expression of C6ORF105 in human macrophages and atherosclerotic lesions. PMID: 25595457
    8. ADTRP polymorphism is associated with the development of coronary atherosclerosis. PMID: 24573017
    9. The single nucleotide polymorphism rs6903956 within the ADTRP gene on chromosome 6p24.1 is significantly associated with coronary artery disease in different ethnic groups of the Singaporean population. PMID: 23337689
    10. This study confirms ADTRP expression and colocalization with TFPI and caveolin-1 in endothelial cell. PMID: 21868574

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    AIG1 family
  • 組織特異性:
    Expressed in cultured endothelial cells and in placenta.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 21214

    OMIM: 614348

    KEGG: hsa:84830

    UniGene: Hs.126409



主站蜘蛛池模板: 人妻激情乱人伦| 久久国产亚洲精选av| 国产原创av中文在线观看| 久久精品国产只有精品96| 亚洲色大成影网站www永久| 国产熟女内射oooo| 风韵少妇性饥渴推油按摩视频| 亚洲精品字幕在线观看| 日本高清视频www| 亚洲日韩一区二区一无码| 国产好吊看视频在线观看| 久久成人伊人欧洲精品| 999久久久免费精品国产| 亚洲精品国产suv一区88| 中文幕无线码中文字夫妻| 欧美性色大片在线观看| 亚洲精品午夜理伦不卡在线观看| 伊人av超碰伊人久久久| 国产毛片久久久久久国产毛片| 全部免费毛片在线播放| 又色又污又爽又黄的网站| 国产白丝无码免费视频| 校花高潮抽搐冒白浆| 久久综合九色综合久99| 亚洲欧美成人a∨观看| 国产粗话肉麻对白在线播放| 亚洲乱码卡一卡二卡新区仙踪木木| 国产亚洲精品资源在线26u| 精品一区二区久久久久久久网站 | 一区二区三区国产精华液| 日本中文字幕乱码免费| 女被男啪到哭的视频网站| 东京道一本热中文字幕| 大陆国产乱人伦| 中国老熟女重囗味hdxx| 成人天堂资源www在线| 国产精品无码av天天爽播放器| 色先锋影音岛国av资源| 最新亚洲人成无码网站| 动漫精品啪啪一区二区三区| 中文在线а√在线天堂中文|