在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Androgen-dependent TFPI-regulating protein (ADTRP)

  • 中文名稱:
    Recombinant Human Androgen-dependent TFPI-regulating protein(ADTRP)
  • 貨號:
    CSB-CF846640HUb3
  • 規(guī)格:
    ¥9720
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    ADTRP
  • Uniprot No.:
  • 別名:
    ADTRP; C6orf105; Androgen-dependent TFPI-regulating protein; Fatty acid esters of hydroxy fatty acids hydrolase ADTRP; FAHFA hydrolase ADTRP
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    in vitro E.coli expression system
  • 分子量:
    46.8kDa
  • 表達區(qū)域:
    1-230aa
  • 氨基酸序列
    MTKTSTCIYHFLVLSWYTFLNYYISQEGKDEVKPKILANGARWKYMTLLNLLLQTIFYGVTCLDDVLKRTKGGKDIKFLTAFRDLLFTTLAFPVSTFVFLAFWILFLYNRDLIYPKVLDTVIPVWLNHAMHTFIFPITLAEVVLRPHSYPSKKTGLTLLAAASIAYISRILWLYFETGTWVYPVFAKLSLLGLAAFFSLSYVFIASIYLLGEKLNHWKWGDMRQPRKKRK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids. Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids. Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro).
  • 基因功能參考文獻:
    1. These data suggest that one molecular mechanism by which androgen confers protection against coronary artery disease is stimulation of ADTRP expression. PMID: 28645652
    2. ADTRP positively regulates PIK3R3 expression, which leads to activation of AKT and up-regulation of MIA3/TANGO1, thereby regulating endothelial cell functions directly relevant to atherosclerosis. PMID: 28341552
    3. ADTRP increases the number of S phase cells during cell cycle. PMID: 27235449
    4. These results indicate that AIG1 and ADTRP are founding members of an evolutionarily conserved class of transmembrane threonine hydrolases involved in bioactive lipid metabolism. PMID: 27018888
    5. association of ADTRP with the pathogenesis of early-onset CAD PMID: 26375920
    6. SNP rs6903956 associated with asymptomatic hyperuricemia susceptibility in Han Chinese PMID: 25928384
    7. Activation of PPARG increases the expression of C6ORF105 in human macrophages and atherosclerotic lesions. PMID: 25595457
    8. ADTRP polymorphism is associated with the development of coronary atherosclerosis. PMID: 24573017
    9. The single nucleotide polymorphism rs6903956 within the ADTRP gene on chromosome 6p24.1 is significantly associated with coronary artery disease in different ethnic groups of the Singaporean population. PMID: 23337689
    10. This study confirms ADTRP expression and colocalization with TFPI and caveolin-1 in endothelial cell. PMID: 21868574

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    AIG1 family
  • 組織特異性:
    Expressed in cultured endothelial cells and in placenta.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 21214

    OMIM: 614348

    KEGG: hsa:84830

    UniGene: Hs.126409



主站蜘蛛池模板: 欧美肥胖老妇bbw| 亚洲国产精品一区二区手机| 97久久婷婷五月综合色d啪蜜芽 | 人人爽人人澡人人人人妻| 特级毛片a片久久久久久| 国产熟妇久久777777| 黄页网站视频| 天天综合色天天综合色h| av无码av不卡一区二区| 精品人妻少妇一区二区| 日韩经典午夜福利发布| 日韩精品一区二区三区中文| 非洲黑人性xxxx精品| 成人国产一区二区三区精品| 午夜精品久久久久久毛片| 全部孕妇毛片| 亚洲成a人v在线蜜臀| 国产激情电影综合在线看| 国产午夜亚洲精品不卡下载| 中文字幕亚洲乱码熟女在线| 国产香蕉尹人在线视频你懂的 | 精品国产成人网站一区在线| 午夜不卡av免费| 青娱乐极品视觉盛宴国产视频| 自拍校园亚洲欧美另类| 日本三级欧美三级人妇视频| 国产专区免费资源网站| 国产丝袜一区视频在线观看| 精品无人区卡一卡二卡三乱码| 大香伊蕉在人线国产最新75| 曰批视频免费30分钟成人| 国产乱码精品一区二区三区中文 | 亚洲成在人线视av| 天美传媒精品1区2区3区| 人妻系列无码专区无码中出| 妓院一钑片免看黄大片| 大陆精大陆国产国语精品| 国内精品乱码卡一卡2卡三卡新区| 好男人在线社区www在线影院| 噜妇插内射精品| 国产三级不卡在线观看视频|