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  4. Recombinant Mouse DNA replication complex GINS protein SLD5 (Gins4)

Recombinant Mouse DNA replication complex GINS protein SLD5 (Gins4)

  • 中文名稱：
    小鼠Gins4重組蛋白
  • 貨號：
    CSB-YP858762MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Gins4重組蛋白
  • 貨號：
    CSB-EP858762MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Gins4重組蛋白
  • 貨號：
    CSB-EP858762MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Gins4重組蛋白
  • 貨號：
    CSB-BP858762MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Gins4重組蛋白
  • 貨號：
    CSB-MP858762MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Gins4
  • Uniprot No.：
  • 別名：
    Gins4; Sld5; DNA replication complex GINS protein SLD5; GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5; N-terminally processed]
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-223
  • 氨基酸序列
    MTEVLDLHGQ DSDGGSEEMV LTPAELIEKL EQAWMNEKFA PELLESKAEI VECVMEQLEH MEENLRRAKK GDLKVSIHRM EMERIRYVLS SYLRCRLMKI EKFFPHILEK EKVRSEGEPS SLSPEEFVFA KEYMDHTETH FKNVALKHMP PNLQKVDLLR AVPKPDLDSY VFLRVKERQE NILVEPEADE QRDYVIDLEV GSQHLIRYKT IAPLVASGAV QLI
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA.
  • 基因功能參考文獻(xiàn)：
    1. Attenuation of SLD5 expression results in marked DNA damage in both normal cells and cancer cells, suggesting that it protects against DNA damage. PMID: 25334017
    2. Requirement of SLD5 for early embryogenesis. PMID: 24244394
    3. These data suggest that PSF1 and SLD5 may cooperate in the proliferation of immature cell populations. PMID: 16338220
  • 亞細(xì)胞定位：
    Nucleus. Chromosome. Cytoplasm.
  • 蛋白家族：
    GINS4/SLD5 family
  • 組織特異性：
    Highly abundant in testis. Weakly expressed in thymus and bone marrow.
  • 數(shù)據(jù)庫鏈接：


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