在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Dihydrolipoyl dehydrogenase, mitochondrial (Dld)

  • 中文名稱:
    小鼠Dld重組蛋白
  • 貨號:
    CSB-YP006928MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Dld重組蛋白
  • 貨號:
    CSB-EP006928MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Dld重組蛋白
  • 貨號:
    CSB-EP006928MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Dld重組蛋白
  • 貨號:
    CSB-BP006928MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Dld重組蛋白
  • 貨號:
    CSB-MP006928MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Dld
  • Uniprot No.:
  • 別名:
    Dld; Dihydrolipoyl dehydrogenase; mitochondrial; EC 1.8.1.4; Dihydrolipoamide dehydrogenase
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    36-509
  • 氨基酸序列
    ADQPI EADVTVIGSG PGGYVAAIKS AQLGFKTVCI EKNETLGGTC LNVGCIPSKA LLNNSHYYHM AHGKDFASRG IEIPEVRLNL EKMMEQKHSA VKALTGGIAH LFKQNKVVHV NGFGKITGKN QVTATKADGS TQVIDTKNIL VATGSEVTPF PGITIDEDTI VSSTGALSLK KVPEKLVVIG AGVIGVELGS VWQRLGADVT AVEFLGHVGG IGIDMEISKN FQRILQRQGF KFKLNTKVTG ATKKSDGKID VSVEAASGGK AEVITCDVLL VCIGRRPFTQ NLGLEELGIE LDPKGRIPVN NRFQTKIPNI YAIGDVVAGP MLAHKAEDEG IICVEGMAGG AVHIDYNCVP SVIYTHPEVA WVGKSEEQLK EEGIEFKIGK FPFAANSRAK TNADTDGMVK ILGHKSTDRV LGAHILGPGA GEMVNEAALA LEYGASCEDI ARVCHAHPTL SEAFREANLA AAFGKPINF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A. In monomeric form may have additional moonlighting function as serine protease. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction.
  • 基因功能參考文獻:
    1. Mitochondrial dihydrolipoamide dehydrogenase is upregulated in response to the brain intermittent hypoxic preconditioning. PMID: 26078703
    2. DLD, malic acid, and fumaric acid can be used for development of cosmeceuticals and nutraceuticals regulating the change of skin metabolism induced by the UVB overexposure. PMID: 25576851
    3. Data show that mitochondrial diaphorases (dihydrolipoamide dehydrogenase) in the liver contribute up to 81% to the NAD(+) pool during respiratory inhibition. PMID: 24391134
    4. Human, mouse, and pig Dld has moonlighting function as a protease in addition to its canonical function as a a dehydrogenase. PMID: 17404228
    5. ATP consumption is demonstrated in respiration-impaired isolated mice and in situ neuronal mitochondria from transgenic mice with dihydrolipoyl succinyltransferase deficiency. PMID: 23475850
    6. Mice that are deficient in dihydrolipoamide dehydrogenase show increased vulnerability to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), malonate and 3-nitropropionic acid, which have been used in models of Parkinson disease and Huntington disease PMID: 15009635

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion matrix. Nucleus. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome.
  • 蛋白家族:
    Class-I pyridine nucleotide-disulfide oxidoreductase family
  • 組織特異性:
    Expressed in liver (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 少妇被爽到高潮在线观看| 精品人伦一区二区三区潘金莲| 大陆精大陆国产国语精品 | 免费毛儿一区二区十八岁| 明星性猛交ⅹxxx乱大交| 国产成人av无码精品天堂| 亚洲a综合一区二区三区| 少妇人妻中文字幕污| 大胸美女被吃奶爽死视频| 99re热这里只有精品视频| 四虎影视精品永久在线观看| 国产三级视频在线播放线观看 | 无码aⅴ精品一区二区三区浪潮 | 国产精品无码素人福利| 国产成人av激情在线播放| 国产精品99久久久久久宅男小说| 欧美巨大巨粗黑人性aaaaaa| 亚洲欧美日本韩国| 久久视频这里只精品99| 人妻插b视频一区二区三区| 无码高潮爽到爆的喷水视频| 人妻系列无码专区久久五月天| 久久精品国产99久久无毒不卡| 国产乱女乱子视频在线播放| 无码少妇精品一区二区免费| 97成人精品国语自产拍| 国产成人无码激情视频| 波多野结衣不打码视频| 柠檬福利精品视频导航| 国产精成a品人v在线播放| 免费女人高潮流视频在线观看| 久久精品中文字幕无码| 天堂最新版资源网| 亚洲精品无码永久中文字幕| 日本不卡一区| 欧美乱码精品一区二区三区| 成 人 免 费 黄 色| 国内自拍五区| 久久久久久国产精品无码超碰| 精品久久久久久777米琪桃花| 国产亚洲综合欧美一区二区 |