在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Varicella-zoster virus Envelope glycoprotein E (gE)-VLPs

  • 中文名稱:
    Recombinant Varicella-zoster virus Envelope glycoprotein E(gE)
  • 貨號(hào):
    CSB-MP362630VAP
  • 規(guī)格:
  • 其他:

產(chǎn)品詳情

  • 基因名:
    gE
  • Uniprot No.:
  • 別名:
    gE; ORF68; Envelope glycoprotein E; gE
  • 種屬:
    Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)
  • 來(lái)源:
    Mammalian cell
  • 表達(dá)區(qū)域:
    31-623aa
  • 氨基酸序列
    SVLRYDDFHTDEDKLDTNSVYEPYYHSDHAESSWVNRGESSRKAYDHNSPYIWPRNDYDGFLENAHEHHGVYNQGRGIDSGERLMQPTQMSAQEDLGDDTGIHVIPTLNGDDRHKIVNVDQRQYGDVFKGDLNPKPQGQRLIEVSVEENHPFTLRAPIQRIYGVRYTETWSFLPSLTCTGDAAPAIQHICLKHTTCFQDVVVDVDCAENTKEDQLAEISYRFQGKKEADQPWIVVNTSTLFDELELDPPEIEPGVLKVLRTEKQYLGVYIWNMRGSDGTSTYATFLVTWKGDEKTRNPTPAVTPQPRGAEFHMWNYHSHVFSVGDTFSLAMHLQYKIHEAPFDLLLEWLYVPIDPTCQPMRLYSTCLYHPNAPQCLSHMNSGCTFTSPHLAQRVASTVYQNCEHADNYTAYCLGISHMEPSFGLILHDGGTTLKFVDTPESLSGLYVFVVYFNGHVEAVAYTVVSTVDHFVNAIEERGFPPTAGQPPATTKPKEITPVNPGTSPLLRYAAWTGGLAAVVLLCLVIFLICTAKRMRVKAYRVDKSPYNQSMYYAGLPVDDFEDSESTDTEEEFGNAIGGSHGGSSYTVYIDKTR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    C-terminal 10xHis-tagged
    If you have specified tag type, please tell us and we will check if it’s possible to develop.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will default ship it in lyophilized form with normal bule ice packs. However, if you request to ship in liquid form, it needs to be shipped with dry ice, please communicate with us in advance and extra fees for dry ice and dry ice box will be charged.
  • 緩沖液:
    Lyophilized from PBS, 6% Trehalose, pH 7.4
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store the protein at -20°C/-80°C upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Envelope glycoprotein that binds to the potential host cell entry receptor IDE.; In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips.; The heterodimer gE/gI serves as a receptor for the Fc part of host IgG. Dissociation of gE/gI from IgG occurs at acidic pH. May thus be involved in anti-VZV antibodies bipolar bridging, followed by intracellular endocytosis and degradation, thereby interfering with host IgG-mediated immune responses.
  • 基因功能參考文獻(xiàn):
    1. Expression and glycan processing of VZV gE were decreased after ATG5 knockdown. PMID: 24198400
    2. gE gene sequences revealed a novel non-synonymous mutations in the e1 and c1 epitopes. PMID: 23757839
    3. GE/gI interaction is critical for VZV neurovirulence. PMID: 20962081
    4. data show that the nonconserved N-terminal region of varicella-zoster virus glycoprotein E is required for VZV tropism for T cells and skin, which is necessary for its life cycle in the human host PMID: 19966293
    5. The precursor nonglycosylated gE form (73 kDa) found in the endoplasmic reticulum binds to Insulin-degrading enzyme. PMID: 19864391
    6. C-terminal domain of varicella-zoster virus glycoprotein E plays a role in viral replication in vitro and skin and T-cell tropism in vivo. PMID: 15507627
    7. HSV deleted for glycoprotein E is impaired for cell-to-cell spread, and VZV gE could not complement this activity. PMID: 19233447

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host cell junction. Host Golgi apparatus membrane; Single-pass membrane protein. Host endosome membrane; Single-pass membrane protein.
  • 蛋白家族:
    Alphaherpesvirinae glycoprotein E family
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: vg:1487709



主站蜘蛛池模板: 国产午夜精品无码| 国产精品嫩草影院久久| 无码精品国产dvd在线观看9久| 国产天堂久久天堂av色综合| 免费的av网站在线观看国产精品| 国产亚洲精品自在久久蜜tv| 欧美亚洲日本高清不卡| 日韩av无码一区二区三区不卡 | 朝鲜女人大白屁股ass| 色婷婷五月综合久久| 亚洲无人区午夜福利码高清完整版 | 国产精品露脸国语对白| 国产真实乱人偷精品视频| 老司机久久99久久精品播放免费| 国语自产偷拍精品视频蜜芽| 无码熟妇人妻av在线电影| 国产一区二区三区乱码在线观看| 7m精品福利视频导航| 伊人婷婷色香五月综合缴缴情| 无码人妻专区免费视频| 国产综合色在线精品| 亚洲成色www久久网站| 在线观看国产精品电影| 久久久水蜜桃国产成人网站| 国产免费久久精品99reswag | 少妇激情一区二区三区视频小说| 欧美牲交a欧美在线| 色噜噜亚洲男人的天堂| 国产98在线 | 免费| 中文无码久久精品| 亚洲综合无码精品一区二区三区| 亚洲人成电影网站色| 欧美性生交活xxxxxdddd| 亚洲国产色播av在线| 国产精品99无码一区二区| 又污又爽又黄的网站| 黄网站成人片免费视频 | 老熟女高潮喷水了| 日本大乳高潮视频在线观看| 人人爽久久涩噜噜噜av| 国产成人亚洲精品无码青青草原 |