在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Sheep Melatonin receptor type 1A (MTNR1A)

  • 中文名稱:
    綿羊MTNR1A重組蛋白
  • 貨號(hào):
    CSB-CF015189SH
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor
  • 種屬:
    Ovis aries (Sheep)
  • 蛋白長(zhǎng)度:
    Full length protein
  • 表達(dá)區(qū)域:
    1-366
  • 氨基酸序列
    MAGRLWGSPGGTPKGNGSSALLNVSQAAPGAGDGVRPRPSWLAATLASILIFTIVVDIVG NLLVVLSVYRNKKLRNAGNVFVVSLAVADLLVAVYPYPLALASIVNNGWSLSSLHCQLSG FLMGLSVIGSVFSITGIAINRYCCICHSLRYGKLYSGTNSLCYVFLIWTLTLVAIVPNLC VGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMLVVVFCYLRIWALVLQVRWKVKPD NKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLVVASDPASMAPRIPEWLFVASYYMA YFNSCLNAIIYGLLNQNFRQEYRKIIVSLCTTKMFFVDSSNHVADRIKRKPSPLIANHNL IKVDSV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
  • 基因功能參考文獻(xiàn):
    1. This study demonstrated that the T allele in the SNP rs403212791 in the MNTR1A gene is associated with a lower total days of anestrus and higher progesterone cycling months and estrus cycling months values in the Rasa Aragonesa breed. PMID: 29475126
    2. Data suggest a positive effect of melatonin treatment on the time of first conception in ewe lambs in Sardinia. The G/G genotype of an SNP in Mtnr1a (G612A; melatonin receptor 1A) influences the reproductive response to melatonin treatment; no influence was found for an SNP in KiSS1 (G1035A; kisspeptin-1) or another SNP in Mtnr1a (C606T). PMID: 25375207
    3. The frequency of single nucleotide polymorphisms of MTNR1A in tropical and temperate climate sheep breeds is reported. PMID: 25708518
    4. The data revealed that the MTNR1A gene polymorphisms influenced spring reproductive resumption in the Sarda sheep breed. PMID: 25132211
    5. Haplotype with T, A and T alleles for SNPs 422, 677 (promoter region) and 612 (Exon 2) showed an increase of the percentage of oestrous cyclic ewes. PMID: 22809454
    6. Report the presence of MT(1) and MT(2) receptors in ram spermatozoa. PMID: 22935156
    7. there was a positive correlation between melatonin receptor type 1A (MTNR1A) allele polymorphisms the reproductive response following synchronisation and artificial insemination in the spring PMID: 21211471
    8. MTNR1A transcripts are expressed in the ovine premammillary hypothalamus and their expression follows a diurnal rhythm PMID: 15470001
    9. The current data, on the MT(1) promoter suggests a general model in which melatonin receptor expression in the mammalian pituitary is determined by the balance between stimulatory and inhibitory transcription factors. PMID: 17337323
    10. Polymorphism of the MTNR1A locus is present in the Sarda sheep breed with a high incidence of the C/C genotype. PMID: 19223130
    11. Ewes with at least 1 M allele are able to conceive at younger ages, better able to breed and conceive out-of-season, and have shorter intervals between first and second lambings than ewes expressing only the m allele. PMID: 19359514

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數(shù)據(jù)庫鏈接:

    KEGG: oas:443022

    UniGene: Oar.506



主站蜘蛛池模板: 成人国产精品一区二区网站公司| 强 暴 疼 哭 处 女 身子视频| 产后漂亮奶水人妻无码| 亚洲精品一区二区三区影院| 97久久精品人人做人人爽| 妺妺窝人体色www婷婷| 人妻夜夜爽天天爽三区| 亚洲天堂2017无码中文| 四虎成人永久在线精品免费| 国语自产精品视频在 视频| 人妻三级日本三级日本三级极| 久久久久久久久久久久久9999 | 在线亚洲中文精品第1页| 中国6一12呦女精品| 18禁美女裸体免费网站| 人妻妺妺窝人体色www聚色窝| 久久精品熟女亚州av麻豆| 国内一区二区三区香蕉aⅴ| 成年轻人网站色直接看| 青青青国产精品一区二区| 国产精品亲子乱子伦xxxx裸| 人妻精品久久久久中文字幕| 亚 洲 成 人 网站在线观看| 国产精品无码翘臀在线看| 亚洲精品中文字幕无码蜜桃| 精品人伦一区二区三区潘金莲 | 国产午夜无码视频在线观看| 8x福利精品第一导航| 成年女人片免费视频播放a| 99热精国产这里只有精品| 国产人久久人人人人爽| 蜜臀aⅴ国产精品久久久国产老师 日韩一区二区三区精品 | 4hu四虎永久在线影院| 五十路熟女丰满大屁股| 亚洲 自拍 另类 欧美 综合| 国产xxxx69真实实拍| 天天爽天天爽天天片a| 国产成人精品一区二区在线小狼| 日日噜噜夜夜狠狠久久蜜桃| 午夜福利午夜福利1000| 顶级少妇做爰视频在线观看|