在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat High affinity immunoglobulin epsilon receptor subunit gamma (Fcer1g)

  • 中文名稱:
    大鼠Fcer1g重組蛋白
  • 貨號(hào):
    CSB-CF008533RA
  • 規(guī)格:
  • 來(lái)源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Fcer1g; Fce1g; High affinity immunoglobulin epsilon receptor subunit gamma; Fc receptor gamma-chain; FcRgamma; Fc-epsilon RI-gamma; IgE Fc receptor subunit gamma; FceRI gamma
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    19-86
  • 氨基酸序列
    LGEPQLCYILDAILFLYGIVLTLLYCRLKIQVRKADIASREKSDAVYTGLNTRNQETYETLKHEKPPQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils priming T-cells toward effector T-helper 2 subset. Associates with pattern recognition receptors CLEC4D and CLEC4E to form a functional signaling complex in myeloid cells. Binding of mycobacterial trehalose 6,6'-dimycolate (TDM) to this receptor complex leads to phosphorylation of ITAM, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes. May function cooperatively with other activating receptors. Functionally linked to integrin beta-2/ITGB2-mediated neutrophil activation. Also involved in integrin alpha-2/ITGA2-mediated platelet activation.
  • 基因功能參考文獻(xiàn):
    1. This study showed that CCL2, NF-kappaB1, RAC2, FCER1G and C1Q may contribute to the generation of neuropathic pain after sciatic nerve injury via immune and defense pathways. PMID: 28033741
    2. The results presented in this paper suggest that the Mincle/MCL/FcepsilonRI-gamma complex is the functionally optimal form for these C-type lectin receptors on the surface of myeloid cells. PMID: 23921530
    3. substitution of FcR-gamma T22 with non-polar amino acids does not interfere with surface expression of the FcvarepsilonRI and its signaling capacity PMID: 22964482
    4. Phospholipase D1 activity by regulating phosphatidic acid formation controls the early signals initiated by FcepsilonRI aggregation that lead to mast cell degranulation. PMID: 15339843
    5. Among the proteins that bind to phosphorylated beta ITAM of the FcepsilonRI-beta are Syk, Grb2, Shc, SHIP, and SHP-1, and binding does not depend on previous cell activation. PMID: 17365510

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    CD3Z/FCER1G family
  • 組織特異性:
    Expressed in leukocytes and pinealocytes. Expression in the pineal gland does not undergo circadian variations.
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 国产69精品久久久久乱码| 麻豆精品国产精华精华液好用吗 | 亚洲国产成人片在线观看无码| 夜夜欢性恔免费视频| 国产一本一道久久香蕉| 文中字幕一区二区三区视频播放 | 小雪尝禁果又粗又大的视频| 波多野结衣乱码中文字幕| 国产午夜人做人免费视频网站| 国产精品一区二区av在线观看| 两个人看的www在线观看| 欧美日韩无套内射另类| 粗大的内捧猛烈进出看视频| 小罗莉极品一线天在线| 高h纯肉无码视频在线观看| 午夜国人精品av免费看| 日本乱妇乱子视频| 国产丝袜美女一区二区三区| 日本人妻人人人澡人人爽| 日韩精品一区二区大桥未久| 国产亚洲精品久久久久久老妇小说 | 老湿机国产福利视频| 天干天干啦夜天干天天爽| 国产精品婷婷久久爽一下| 国产成人+亚洲欧洲+综合| 人人澡人人澡人人看添av| 国产曰批免费视频播放免费| 成人免费无码av| 久久久精品区二区三区免费| 爆乳护士一区二区三区在线播放| 国产一起色一起爱| 免费无码又爽又刺激高潮| 亚洲狠狠色丁香婷婷综合| 国产成年女人毛片80s网站| 久久丫精品久久丫| 2019最新久久久视频精品| 无码啪啪熟妇人妻区| 欧美深度肠交惨叫| 久章草国语自产拍在线观看| 成人无码精品免费视频在线观看| 久久精品中文字幕一区|