在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Mgat5)

  • 中文名稱:
    大鼠Mgat5重組蛋白
  • 貨號:
    CSB-CF147087RA
  • 說明書:
  • 規(guī)格:
    ¥12863
  • 其他:

產(chǎn)品詳情

  • 基因名:
    Mgat5
  • Uniprot No.:
  • 別名:
    Mgat5Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; EC 2.4.1.155; Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GlcNAc-T V; GNT-V; Mannoside acetylglucosaminyltransferase 5; N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; Secreted beta-1,6-N-acetylglucosaminyltransferase V; Secreted GNT-V)]
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length
  • 來源:
    in vitro E.coli expression system
  • 表達區(qū)域:
    1-740
  • 氨基酸序列
    MAFFSPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYDLKKTLAVLLDNILQRIGKLESKVDNLVNGTGANSTNSTTAVPSLVSLEKINVADIINGVQEKCVLPPMDGYPHCEGKIKWMKDMWRSDPCYADYGVDGTSCSFFIYLSEVENWCPRLPWRAKNPYEEADHNSLAEIRTDFNILYGMMKKHEEFRWMRLRIRRMADAWIQAIKSLAEKQNLEKRKRKKILVHLGLLTKESGFKIAETAFSGGPLGELVQWSDLITSLYLLGHDIRISASLAELKEIMKKVVGNRSGCPTVGDRIVELIYIDIVGLAQFKKTLGPSWVHYQCMLRVLDSFGTEPEFNHASYAQSKGHKTPWGKWNLNPQQFYTMFPHTPDNSFLGFVVEQHLNSSDIHHINEIKRQNQSLVYGKVDSFWKNKKIYLDIIHTYMEVHATVYGSSTKNIPSYVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIANGCAFLNPKFNPPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNREEVEDAVKAILNQKIEPYMPYEFTCEGMLQRINAFIEKQDFCHGQVMWPPLSALQVKLAEPGQSCKQVCQESQLICEPSFFQHLNKEKDLLKYKVICQSSELYKDILVPSFYPKSKHCVFQGDLLLFSCAGAHPTHQRICPCRDFIKGQVALCKDCL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Catalyzes the addition of N-acetylglucosamine (GlcNAc) in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. Catalyzes an important step in the biosynthesis of branched, complex-type N-glycans, such as those found on EGFR, TGFR (TGF-beta receptor) and CDH2. Via its role in the biosynthesis of complex N-glycans, plays an important role in the activation of cellular signaling pathways, reorganization of the actin cytoskeleton, cell-cell adhesion and cell migration. MGAT5-dependent EGFR N-glycosylation enhances the interaction between EGFR and LGALS3 and thereby prevents rapid EGFR endocytosis and prolongs EGFR signaling. Required for efficient interaction between TGFB1 and its receptor. Enhances activation of intracellular signaling pathways by several types of growth factors, including FGF2, PDGF, IGF, TGFB1 and EGF. MGAT5-dependent CDH2 N-glycosylation inhibits CDH2-mediated homotypic cell-cell adhesion and contributes to the regulation of downstream signaling pathways. Promotes cell migration. Contributes to the regulation of the inflammatory response. MGAT5-dependent TCR N-glycosylation enhances the interaction between TCR and LGALS3, limits agonist-induced TCR clustering, and thereby dampens TCR-mediated responses to antigens. Required for normal leukocyte evasation and accumulation at sites of inflammation. Inhibits attachment of monocytes to the vascular endothelium and subsequent monocyte diapedesis.; Promotes proliferation of umbilical vein endothelial cells and angiogenesis, at least in part by promoting the release of the growth factor FGF2 from the extracellular matrix.
  • 基因功能參考文獻:
    1. These results strongly suggest that N-acetylglucosaminyltransferase V functioning as a specific endogenous role of NGF receptor function, which appear to be due, at least in part, to the promotion of differentiation. PMID: 18343992
  • 亞細(xì)胞定位:
    Golgi apparatus membrane; Single-pass type II membrane protein.; [Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A]: Secreted.
  • 蛋白家族:
    Glycosyltransferase 18 family
  • 組織特異性:
    Detected in kidney (at protein level). Detected in kidney.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 男男啪啪激烈高潮cc漫画免费| 国产精品va在线观看h| 国产人成无码视频在线1000| 99久久久无码国产精品不卡| 艳妇臀荡乳欲伦交换在线播放| 免费h动漫无码网站| 久久人人97超碰caoporen| 日本阿v网站在线观看中文| 小sao货水好多真紧h无码视频| 大j8黑人w巨大888a片| 成人免费精品网站在线观看影片| 日日摸天天爽天天爽视频| 曰本女人与公拘交酡免费视频| 欧美综合精品久久久久成人影院| 久久精品国产精品亚洲蜜月| 国产成人精品123区免费视频| 少妇的肉体k8经典| 亚洲aⅴ天堂av天堂无码app| 性饥渴的农村熟妇| 四虎成人精品国产永久免费无码| 国产aⅴ精品一区二区三区尤物 | 忘忧草社区中文字幕www| 一区二区视频日韩免费| 日韩人妻精品无码一区二区三区| 狠狠色狠狠色综合日日不卡| 亚洲精品一品区二品区三区| 影视av久久久噜噜噜噜噜三级| 欧美老妇交乱视频在线观看 | 欧美日激情日韩精品嗯| 无码专区—va亚洲v专区| 久久午夜夜伦鲁鲁片免费无码| 精品国精品自拍自在线| 忘忧草社区在线资源www| 国产精品毛片无码| 西西人体大胆4444www| 免费精品国偷自产在线2020| 特级毛片在线大全免费播放| 日韩人妻无码精品免费shipin| 99999久久久久久亚洲| 中文字幕av一区二区三区| 免费看成人欧美片爱潮app|