在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rabbit Potassium channel subfamily K member 1 (KCNK1)

  • 中文名稱:
    小圓錐花果KCNK1重組蛋白
  • 貨號:
    CSB-CF722629RB
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    KCNK1
  • Uniprot No.:
  • 別名:
    KCNK1; Potassium channel subfamily K member 1
  • 種屬:
    Oryctolagus cuniculus (Rabbit)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-336
  • 氨基酸序列
    MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK RRFVEEHECLSEQQLEQFLGRVLEANNYGVSVRSNASGNWNWDFASALFFASTVLSTTGY GHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRVTVHVTRRPVLYFHVRWGFSKQVVA IVHAVLLGLITVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQK FRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQLS FSSITEQAAGMKEDQKQNEPFVATPSSACADGPANH
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium channel activity, when expressed in heterologous systems, and can function as weakly inward rectifying potassium channel. Channel activity is modulated by activation of serotonin receptors. Heterodimeric channels containing KCNK1 and KCNK2 have much higher activity, and may represent the predominant form in astrocytes. Heterodimeric channels containing KCNK1 and KCNK3 or KCNK9 have much higher activity. Heterodimeric channels formed by KCNK1 and KCNK9 may contribute to halothane-sensitive currents. Mediates outward rectifying potassium currents in dentate gyrus granule cells and contributes to the regulation of their resting membrane potential. Contributes to the regulation of action potential firing in dentate gyrus granule cells and down-regulates their intrinsic excitability. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled receptors, such as F2R and CNR1. Required for normal ion and water transport in the kidney. Contributes to the regulation of the resting membrane potential of pancreatic beta cells. The low channel activity of homodimeric KCNK1 may be due to sumoylation. The low channel activity may be due to rapid internalization from the cell membrane and retention in recycling endosomes.
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Recycling endosome. Cell junction, synapse, synaptic cell membrane. Cytoplasmic vesicle. Perikaryon. Cell projection, dendrite. Cell projection. Apical cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Two pore domain potassium channel (TC 1.A.1.8) family
  • 組織特異性:
    Expressed in renal distal tubules, especially in cortical collecting duct and cortical thick ascending limb, with lower levels in the connecting tubule.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲美女国产精品久久久久久久久| 色妺妺视频网| 粉色午夜视频| 国产免费无遮挡吸奶头视频 | 午夜一区一品日本| 黄桃av无码免费一区二区三区| 天堂中文最新版在线官网在线| 亚洲国产精品国语在线| 色欲av久久综合人妻无码| 在线观看无码av网址| 一区二区三区无码高清视频| 无码中文字幕色专区| 亚洲第一网站男人都懂| 精品国产一区二区三区av孞弋| av永久天堂一区| 一区二区三区无码高清视频| 又大又黄又粗又爽的免费视频| 无码精品a∨在线观看无广告| 12裸体自慰免费观看网站| 羞国产在线拍揄自揄视频| 亚洲 高清 成人 动漫| 国产一区二区在线影院| 中国人妻被两个老外三p| 国产在线视频主播区| 日韩经典午夜福利发布| 国语做受对白xxxxx在线| 噜噜色综合天天综合网mp3| 亚洲国产精品一区二区www| 精品国产乱码久久久人妻| 99久热re在线精品视频| 亚洲欧洲成人a∨在线| 国产午夜片无码区在线播放| 高潮添下面视频免费看| 免费国产乱理伦片在线观看| 99热成人精品国产免费 | 搡女人真爽免费视频大全| 亚洲人成人网站色www| 97人妻无码专区| 丰满少妇人妻无码| 女人被狂躁c到高潮喷水一区二区| 麻花传媒mv在线观看|