Recombinant Mycobacterium smegmatis GDP-mannose-dependent alpha- (1-2)-phosphatidylinositol mannosyltransferase

in vitro E.coli expression system

中文名稱：

Recombinant Mycobacterium smegmatis GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase
貨號：

CSB-CF368000MVX
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

pimA
Uniprot No.：

A0QWG6
別名：

pimA; MSMEG_2935; MSMEI_2861; Phosphatidyl-myo-inositol mannosyltransferase; Alpha-mannosyltransferase; GDP-mannose-dependent alpha-(1-2-phosphatidylinositol mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase
種屬：

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
蛋白長度：

full length protein
表達區域：

1-386
氨基酸序列

MRIGMVCPYSFDVPGGVQSHVLQLAEVLRDAGHEVSVLAPASPHVKLPDYVVSGGKAVPI PYNGSVARLRFGPATHRKVKKWIAEGDFDVLHIHEPNAPSLSMLALQAAEGPIVATFHTS TTKSLTLSVFQGILRPYHEKIIGRIAVSDLARRWQMEALGSDAVEIPNGVDVASFADAPL LDGYPREGRTVLFLGRYDEPRKGMAVLLAALPKLVARFPDVEILIVGRGDEDELREQAGD LAGHLRFLGQVDDATKASAMRSADVYCAPHLGGESFGIVLVEAMAAGTAVVASDLDAFRR VLADGDAGRLVPVDDADGMAAALIGILEDDQLRAGYVARASERVHRYDWSVVSAQIMRVY ETVSGAGIKVQVSGAANRDETAGESV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). In contrary to PimB, the mannosyltransferase PimA is unable to transfer a mannose residue to the position 6 of the phosphatidyl-myo-inositol of PIM1.
基因功能參考文獻：
1. Data indicate that mannosyltransferase PimA (MsPimA; MSMEG_2935) exhibits weak mechanical stability albeit displaying beta-sheet topology expected to unfold at much higher forces. PMID: 23963451
亞細胞定位：

Cell membrane; Peripheral membrane protein; Cytoplasmic side.
蛋白家族：

Glycosyltransferase group 1 family, Glycosyltransferase 4 subfamily
數據庫鏈接：

KEGG: msb:LJ00_14605

STRING: 246196.MSMEG_2935