在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Zinc transporter 7 (Slc30a7)

  • 中文名稱:
    小鼠Slc30a7重組蛋白
  • 貨號:
    CSB-CF872871MO
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Slc30a7; Znt7; Zntl2; Zinc transporter 7; ZnT-7; Solute carrier family 30 member 7; Znt-like transporter 2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-378
  • 氨基酸序列
    MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSN CLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAF FIFSEGVERALAPPDVHHERLLLVSILGFVVNLVGIFVFNHGGHGHSHGSGHGHSHSLFN GALDHSHGHEDHCHSHEAKHGAAHSHDHDHAHGHGHLHSHDGPSFKATAGPSRQILQGVF LHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTP PSLENTLPQCYQRVQQLQGVYNLQEQHFWTLCSDVYVGTLKLVVAPDADARWILSQTHNI FTQAGVRQLYVQIDFAAM
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP.
  • 基因功能參考文獻:
    1. A role for ZnT7 in adipocyte lipogenesis: reduction of Znt7 expression affects lipid accumulation in adipocytes. PMID: 26524605
    2. In Znt7 knockout mice, the body weight and fat deposit was significantly linked to a locus on chromosome 7 ranging from 64.3 to 78.3 Mb. PMID: 24770585
    3. ZnT7 promotes cell survival via two distinct signaling pathways involving activation of the PI3K/Akt-mediated survival pathway and activation of MAPK/ERK pathway. PMID: 23403124
    4. Znt7-null mice are more susceptible to diet-induced glucose intolerance and insulin resistance PMID: 22854958
    5. A null-mutation of the Znt7 gene accelerates prostate tumor formation in TRAMP mice. PMID: 21621325
    6. novel member of zinc transporter family that accumulates zinc in the Golgi apparatus PMID: 12446736
    7. ZnT5(-)ZnT7(-/-) cells showed exacerbation of the unfolded protein response as did the wild-type cells cultured under a zinc-deficient condition, revealing that both complexes play a role in homeostatic maintenance of secretory pathway function PMID: 16636052
    8. These observations strongly suggest that ZnT7 may play critical roles in retinal zinc homeostasis and that chelatable zinc pools may have multiple functions in the retina. PMID: 17113933
    9. ZNT7 has essential functions in dietary zinc absorption and in regulation of body adiposity. PMID: 17954933
    10. These observations support the notion that ZnT7 may participate in zinc transport, storage, and incorporation of zinc into zinc-binding proteins in the Golgi apparatus of mouse SCG neurons. PMID: 18499530
    11. ZNT7 and chelatable zinc were distributed in different cell populations. ZNT7 may be involved in zinc transportation into the Golgi apparatus for protein packaging in the mouse testis PMID: 19012241
    12. Immunoelectron microscopic study showed that ZNT7 was localized to the membrane of the Golgi apparatus in the somas of the Purkinje cells, Bergmann glial cells, and granule cells throughout the cerebellar cortex. PMID: 19283665

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
  • 組織特異性:
    Highly expressed in liver, spleen, duodenum and part of the jejunum of small intestine (at protein level). Moderately expressed in kidney, lung, and brain. Barely detectable in heart.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 久久精品国产精品久久久| 精品国产美女福到在线不卡| 精品欧美一区二区在线观看| 成年无码av片在线| 久久婷婷五月综合色首页| 日日大香人伊一本线久| 国产亚洲美女精品久久久2020| 亚洲国产无线乱码在线观看| 人妻少妇精品视频无码综合| 国内免费视频成人精品| 亚洲一区av无码专区在线观看| 99久久久无码国产aaa精品| 国产素人在线观看人成视频| 13小箩利洗澡无码视频网站 | 亚洲午夜福利在线视频| www污污污抽搐喷潮com| 久久伊人精品波多野结衣| 色香阁综合无码国产在线| 玩弄丰满少妇xxxxx性多毛| 韩国美女视频黄是免费| 亚洲中文字幕无码久久2020| 无码精品人妻一区二区三区98| 毛片免费视频| 国产麻豆剧果冻传媒一区| 亚洲午夜无码久久久久小说| 色婷婷av一区二区三区浪潮| 曰曰摸夜夜添夜夜添高潮出水| 中文在线а√在线天堂中文| 无码专区手机在线播放| 国产成人无码aa精品一区| а√天堂资源官网在线资源| 免费看国产精品3a黄的视频| 国产美女久久久亚洲综合| 欧美内射rape视频| 最新国产精品拍自在线观看| 亚洲国产成人久久一区| 亚洲人ⅴsaⅴ国产精品| 国产精品久久久久永久免费看| 日本高清色www网站色噜噜噜| 亚洲日韩欧美在线成人| 亚洲一区二区三区写真|