在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Translocation protein SEC63 homolog (Sec63)

  • 中文名稱:
    小鼠Sec63重組蛋白
  • 貨號(hào):
    CSB-CF837736MO
  • 規(guī)格:
  • 來(lái)源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Sec63; Sec63l; Translocation protein SEC63 homolog
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    2-760
  • 氨基酸序列
    AGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYRL RLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIK KQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPA WIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNM DMKRLIMVLAGASEFDPQYNKDSTSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKA RVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLA SLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRH SLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAE VFEKEQSICAAEEQPTEDGQSDANKIKAKGGWQQKNKGPKKMPKSKKKKPLKKKPTTVPL PQAKQQKQKQANGVVGSEAAIKEEEDDISDKGSDSEEEETNRDSQSEKEDGSDRESDREQ DEKQSKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQ TLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKP VPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEGGD
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Mediates cotranslational and post-translational transport of certain precursor polypeptides across endoplasmic reticulum (ER). Proposed to play an auxiliary role in recognition of precursors with short and apolar signal peptides. May cooperate with SEC62 and HSPA5/BiP to facilitate targeting of small presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia.
  • 基因功能參考文獻(xiàn):
    1. SEC63 function regulates IRE1alpha/XBP1 activation. SEC63 and XBP1 are required for GPS cleavage and maturation of PC1, protecting against polycystic disease. PMID: 25844898
    2. The pro-carcinogenic growth behavior of hepatocytes with low SEC63 expression in the murine model indicates a potential role for SEC63 in hepatocarcinogenesis in general. PMID: 23537056
    3. Knockout of the murine Sec63 gene inhibits transport of precursor proteins into the endoplasmic reticulum. PMID: 22375059
    4. SEC63 gene expression is up-regulated and predominantly localized in mouse decidual cells during days 5-8 of pregnancy. PMID: 19208265
  • 亞細(xì)胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 組織特異性:
    Expressed in kidney (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 少妇高潮毛片色欲ava片| 少妇人妻偷人激情视频| 国产成人精品123区免费视频| 人妻熟女一二三区夜夜爱| 特级欧美插插插插插bbbbb| 男女啪啦猛视频免费| 性一交一黄一片| 欧美一区二区三区久久综合| 国产xxxx做受视频| 国产在线高清视频无码| 扒开双腿疯狂进出爽爽爽视频| 久久综合色之久久综合| 色综合 图片区 小说区| 艳妇乳肉豪妇荡乳在线观看 | 日欧一片内射va在线影院| 国产日韩精品一区二区三区在线| 美女被张开双腿日出白浆| 2021无码天堂在线| 国产色爱av资源综合区| 奇米影视777四色狠狠| 亚洲vs成人无码人在线观看堂| 精品欧美成人高清在线观看| 真人性囗交69视频| 熟女人妻av粗壮巨龙| 午夜人性色福利无码视频在线观看| 国产边打电话边被躁视频| 久久综合狠狠色综合伊人| 99久久国产露脸精品| 欧美欧洲成本大片免费| 麻豆亚洲一区| 98视频精品全部国产| 青青草在在观免费福利线观看| 情侣做性视频在线播放| 人人做人人妻人人精| 婷婷色综合视频在线观看| 国产成人无码精品久久久露脸| 国产又粗又猛又大爽老大爷| 亚洲精品无码成人片| 鲁鲁狠狠狠7777一区二区 | 亚洲精品久久区二区三区蜜桃臀| 日日婷婷夜日日天干|