在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Tetraspanin-12 (Tspan12)

  • 中文名稱:
    小鼠Tspan12重組蛋白
  • 貨號:
    CSB-CF805915MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    Tspan12
  • Uniprot No.:
  • 別名:
    Tspan12; Tm4sf12; Tetraspanin-12; Tspan-12; Transmembrane 4 superfamily member 12
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-305
  • 氨基酸序列
    MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGTLLVIFCVELACGVWTYEQEVM VPVQWSDMVTLKARMTNYGLPRYRWLTHAWNYFQREFKCCGVVYFTDWLEMTEMDWPPDS CCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMIL TITLLWALYYDRREPGTDQMLSLKNDTSQHLSCHSVELLKPSLSRIFEHTSMANSFNTHF EMEEL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulator of cell surface receptor signal transduction. Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP). Activates MMP14/MT1-MMP-dependent cleavage activity. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1).
  • 基因功能參考文獻:
    1. TSPAN12 promotes chemoresistance and proliferation of small cell lung carcinoma under the regulation of miR-495. PMID: 28302484
    2. Data indicate that Norrin multimers and TSPAN12 cooperatively promote multimerization of FZD4 and its associated proteins to elicit physiological levels of signaling. PMID: 19837033
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Tetraspanin (TM4SF) family
  • 組織特異性:
    Expressed in the neonatal retinal vasculature but not other retinal tissues. Also detected in the neonatal meningeal vasculature and in nonvascular cell types, such as the smooth muscle cells in the neonatal intestine.
  • 數據庫鏈接:

    KEGG: mmu:269831

    UniGene: Mm.21950



主站蜘蛛池模板: 欧美日韩无砖专区一中文字| 青青草国产午夜精品| 欧美不卡无线在线一二三区观| 久久国产精品日本波多野结衣| 伊人久久大香线焦av综合影院| 污污污污污污www网站免费| 久久96国产精品久久久| 色偷偷亚洲精品一区二区| 亚洲中文在线播放一区| 超caopor在线公开视频| 国产精品免费看久久久无码| 欧美老熟妇xb水多毛多| 亚洲精品无码av黄瓜影视| 国产精品女主播在线视频| 极品新婚夜少妇真紧| 久久国产精品福利一区二区三区| 麻批好紧日起要舒服死了| 欧美嫩交一区二区三区| 国色天香成人一区二区| 亚洲国产区男人本色| 阳茎伸入女人阳道视频免费| 国产成人精品自在线导航| 成人无码α片在线观看不卡| 国产九九九九九九九a片| 欧美老熟妇乱大交xxxxx| 国产日韩另类综合11页| 亚洲色欲色欲综合网站| 国产精品自产拍高潮在线观看| 免费国产a国产片高清网站| 国产一区二区不卡在线看| 日韩精品成人一区二区三区 | 无码天堂亚洲国产av麻豆| 男人猛躁进女人免费播放 | 黄网站成人片免费视频| 免费看成人毛片无码视频| 大乳丰满人妻中文字幕日本| 硬了进去湿好大娇喘视频| 无码纯肉动漫在线观看| 欧美牲交40_50a欧美牲交aⅴ| 久久久婷婷五月亚洲97号色| 天天拍夜夜添久久精品|