在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse T-cell surface antigen CD2 (Cd2)

  • 中文名稱:
    Recombinant Mouse T-cell surface antigen CD2(Cd2)
  • 貨號:
    CSB-CF004894MO
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Cd2; Ly-37; T-cell surface antigen CD2; LFA-2; LFA-3 receptor; Lymphocyte antigen 37; T-cell surface antigen T11/Leu-5; CD antigen CD2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區(qū)域:
    23-344
  • 氨基酸序列
    RDNETIWGVLGHGITLNIPNFQMTDDIDEVRWVRRGTLVAEFKRKKPPFLISETYEVLANGSLKIKKPMMRNDSGTYNVMVYGTNGMTRLEKDLDVRILERVSKPMIHWECPNTTLTCAVLQGTDFELKLYQGETLLNSLPQKNMSYQWTNLNAPFKCEAINPVSKESKMEVVNCPEKGLSFYVTVGVGAGGLLLVLLVALFIFCICKRRKRNRRRKDEELEIKASRTSTVERGPKPHSTPAAAAQNSVALQAPPPPGHHLQTPGHRPLPPGHRTREHQQKKRPPPSGTQIHQQKGPPLPRPRVQPKPPCGSGDGVSLPPPN
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
  • 基因功能參考文獻:
    1. Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes PMID: 26438525
    2. CD2 stimuli were mandatory for Treg cell survival with reduced Bim expression, but CD2 may not function as a direct receptor for molecules on stromal cells. PMID: 23278598
    3. CD2 is important for the efficient development of CD4 single-positive thymocytes and TCR-dependent activation of mature CD4 lymph node T cells, but does not direct a particular helper T cell subset polarity. PMID: 11801645
    4. This antigen is a dominant target for heart allograft responses. PMID: 12201362
    5. molecular mechanism of heterophilic adhesion between the murine T-cell adhesion glycoprotein CD2 and its ligand CD48 PMID: 12356317
    6. Despite normal T cell numbers, mice deficient in the costimulatory molecules CD2 and CD28 spontaneously develop Pneumocystis carinii pneumonia. PMID: 12902500
    7. autoimmunity may be mediated by a combination of genes in the SLAM/CD2 family cluster PMID: 15589166
    8. Analysis of the ligand-receptor pairs involved in induction of germline transcripts (Igamma2a) necessary for switch recombination revealed that expression of CD48 on B cells and ligands CD2 and CD244 on NK cells are able to stimulate Igamma2a PMID: 15778370
    9. CD2 deficient mice are more resistant to T. gondii infection than wild type mice PMID: 17696249
    10. nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse PMID: 18826951
    11. CD244 inhibition and activation depends on CD2 and phospholipase C-gamma1 PMID: 19586919

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Detected in thymus and spleen.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 日本一区二区三区免费播放视频站 | 亚洲成av人片一区二区梦乃| 男女啪啪永久免费观看网站| 国精产品一二三区传媒公司| 亚洲综合色丁香婷婷六月图片| 国产国拍精品av在线观看| 亚洲中文欧美在线视频| 亚洲综合成人av一区在线观看| 国产丝袜一区视频在线观看| 国产午夜精品av一区二区| 人人妻人人澡人人爽| 国产 一二三四五六| 粗壮挺进人妻水蜜桃成熟漫画| 久久―日本道色综合久久| 少妇裸体性生交| 成人免费无码大片a毛片抽搐色欲 荫蒂被男人添的好舒服爽免费视频 | 国产精品白丝喷水在线观看| 精品无码日韩一区二区三区不卡| 国产精品国产三级国av| 国产激情电影综合在线看| 国产精品视频永久免费播放| 欧美人与动牲交zooz乌克兰| 热99re久久精品天堂| 无码抽搐高潮喷水流白浆| 熟女少妇人妻中文字幕| 午夜无码片在线观看影院| 国产成人福利美女观看视频| 国产草莓视频无码a在线观看| 亚洲中文字幕久久精品无码喷水| 无码h片在线观看网站| 欧美又粗又大又黄的片| 亚洲精品国偷自产在线99人热| 久久99国产精品久久99| 老鲁夜夜老鲁| 四川老熟女下面又黑又肥| 国产成人免费永久播放视频平台| 国产香蕉尹人在线观看视频| 老太婆性杂交视频| 婷婷丁香五月六月综合激情啪| 亚洲精品乱拍国产一区二区三区| 国产性天天综合网|