在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Sphingolipid delta (4)-desaturase DES1 (Degs1)

  • 中文名稱:
    Recombinant Mouse Sphingolipid delta(4)-desaturase DES1(Degs1)
  • 貨號:
    CSB-CF006708MO
  • 說明書:
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    Degs1
  • Uniprot No.:
  • 別名:
    Degs1; Degs; Des1; Mdes; Sphingolipid delta(4-desaturase DES1; Degenerative spermatocyte homolog 1; Dihydroceramide desaturase-1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-323
  • 氨基酸序列
    GSRVSREEFEWVYTDQPHAARRKEILAKYPEIKSLMKPDHNLIWIVAMMLLVQLASFYLV KDLDWKWVIFWSYVFGSCLNHSMTLAIHEISHNFPFGHHKALWNRWFGMFANLSLGVPYS ISFKRYHMDHHRYLGADKIDVDIPTDFEGWFFCTTFRKFVWVILQPLFYAFRPLFINPKP ITYLEIINTVIQITFDIIIYYVFGVKSLVYMLAATLLGLGLHPISGHFIAEHYMFLKGHE TYSYYGPLNLLTFNVGYHNEHHDFPNVPGKNLPMVRKIASEYYDDLPHYNSWIKVLYDFV TDDTISPYSRMKRPPKGNEILE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols.
  • 基因功能參考文獻:
    1. genetic ablation of DEGS1 in preadipocytes prevented adipogenesis and decreased lipid accumulation. This was associated with elevated oxidative stress, cellular death, and blockage of the cell cycle. PMID: 25352638
    2. The role of Degs1 in the hypoxic mouse heart.Hand2 and NFATC physically interact on the DEGS1 promoter. PMID: 23672204
    3. Ablation of dihydroceramide desaturase 1 simultaneously stimulates anabolic and catabolic signaling. PMID: 23547262
    4. Des1 ablation activated pro-survival and anabolic signaling intermediates (e.g. Akt/PKB, mTOR, MAPK, etc.) and provided protection from apoptosis caused by etoposide. PMID: 22984457
    5. overexpression of DEGS1 or DEGS2 attenuates the DHC accumulation and increased cell proliferation during hypoxia PMID: 21914808
    6. analysis of dihydroceramide desaturase regulation by palmitate versus monounsaturated fatty acids and its implications for insulin resistance PMID: 21454530
    7. Data show that CS-mediated SCC lethality was mitigated in irradiated gain-of-function Rad50(s/s) mice, and epistasis studies order Rad50 upstream of Mre11. PMID: 20086180
    8. GT11 is the first specific inhibitor of dihydroceramide desaturase described so far PMID: 15371559

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion membrane. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Fatty acid desaturase type 1 family, DEGS subfamily
  • 組織特異性:
    Detected in testis. Detected in pachytene spermatocytes and round spermatids. Expressed in retina and retinal pigment epithelium by Mueller cells (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 午夜爽爽爽男女免费观看麻豆国产| 色综合久久久久综合体桃花网| 亚洲综合av色婷婷| 果冻传媒一区二区天美传媒| 在线观看无码av网址| 好吊色欧美一区二区三区视频| 中文字幕丰满孑伦无码精品| 亚洲日韩日本中文在线| 国产女人喷潮视频在线观看| 国产在线精品一区二区三区不卡| 51妺嘿嘿午夜福利| 久久永久免费专区人妻精品| 国产乱码二卡3卡四卡| 国产欧美久久一区二区| 青青草av一区二区三区| 国产成人无码精品久久涩吧| 人妻丰满熟妇av无码区app| 国产精品久久久久久一区二区三区| 亚洲综合色婷婷七月丁香| 52综合精品国产二区无码| 国产呻吟久久久久久久92| 天天爽夜夜爽夜夜爽精品视频| 人妻护士在线波多野结衣| 午夜三级a三级三点在线观看| 18禁高潮出水呻吟娇喘蜜芽| 中文精品久久久久人妻| 欧美国产日韩a欧美在线观看 | 人妻无码久久一区二区三区免费| av在线播放无码线| 国产亚洲精品第一综合不卡| 肉体裸交137日本大胆摄影| 色噜噜av亚洲色一区二区| 国产yw8825免费观看网站| 国产片av片永久免费观看| 国产色婷婷亚洲99精品小说| 凹凸精品熟女在线观看| 国产精成a品人v在线播放 | 又爽又黄又无遮挡的激情视频 | 国产又粗又硬又大爽黄老大爷视| 亚洲国产成人精品无码区在线软件| 6080亚洲人久久精品|