在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Sodium/potassium-transporting ATPase subunit beta-1 (Atp1b1)-VLPs

  • 中文名稱:
    Recombinant Mouse Sodium/potassium-transporting ATPase subunit beta-1 (Atp1b1)-VLPs
  • 貨號:
    CSB-MP002326MO
  • 規(guī)格:
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    (Sodium/potassium-dependent ATPase subunit beta-1)
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length
  • 來源:
    Mammalian cell
  • 表達區(qū)域:
    1-304aa
  • 氨基酸序列
    MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISELKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIIRFLEKYKDSAQKDDMIFEDCGNVPSEPKERGDINHERGERKVCRFKLDWLGNCSGLNDDSYGYREGKPCIIIKLNRVLGFKPKPPKNESLETYPLMMKYNPNVLPVQCTGKRDEDKDKVGNIEYFGMGGYYGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTVDTEIRVECKAYGENIGYSEKDRFQGRFDVKIEIKS-
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 10xHis-tagged
    If you have specified tag type, please tell us and we will check if it's possible to develop.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from PBS, 6% Trehalose, pH 7.4.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80℃. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex. Repeated freezing and thawing is not recommended.Store the protein at -20℃/-80℃ upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.; Involved in cell adhesion and establishing epithelial cell polarity.
  • 基因功能參考文獻:
    1. FXYD5 mediates metastatic progression through regulation of the beta Na(+)-K(+)-ATPase subunit in the 4T1 mouse breast cancer model. PMID: 28515087
    2. Activities of AE1 and the sodium pump are coregulated in kidney. PMID: 25012180
    3. Atp1b1 was highly expressed in luminal epithelium during peri-implantation and upregulated by progesterone. PMID: 23534996
    4. Beta(1) is the sole expressed beta-subunit in the diaphragm throughout development, and in the hindlimb muscles at birth. PMID: 12397396
    5. the beta1 subunit of the Na/K-ATPase is required for blastocyst formation and also for maintaining a normal Na/K-ATPase distribution and localization of tight junction-associated polypeptides during preimplantation development PMID: 17317668
    6. These data suggest that CLN3 is involved in the regulation of plasma membrane fodrin cytoskeleton and consequently, the plasma membrane association of Na(+), K(+) ATPase. PMID: 18621045
    7. Inhibition of the Atp1b1 isoenzyme of the sodium potassium exchanging ATPase by 8-methoxycoumestrol is reported. PMID: 19487957
    8. Na,K-beta(1) plays an essential role in regulating cardiac contractility and that its loss is associated with significant pathophysiology of the heart. PMID: 19683723

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Cell membrane, sarcolemma.
  • 蛋白家族:
    X(+)/potassium ATPases subunit beta family
  • 組織特異性:
    Expressed in cardiac muscle and in flexor digitorum brevis (FDB) muscle (at protein level). Expressed in a circadian manner in the kidney and aorta (at protein level).
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 天天影视网天天综合色| 日韩毛片在线视频x| 亚洲一区二区三区丝袜| 欧美精品18videosex性欧美| 任你躁久久精品6| 亚洲欧美成人中文日韩电影网站| 成av人片一区二区三区久久| 国产精品嫩草影院av| 麻豆国产在线精品国偷产拍| 欧美精品黑人粗大免费| 亚洲欧美日韩综合俺去了| 亚洲高清毛片一区二区| 久久久久成人精品免费播放动漫 | 国产又猛又黄又爽| 国产一区二区三区在线电影| 96亚洲精华国产精华精华液| 久久精品蜜芽亚洲国产av| 边啃奶头边躁狠狠躁| 五月综合色婷婷在线观看| 国产免费网站看v片在线无遮挡| 亚洲国产中文在线二区三区免| 无码人妻aⅴ一区二区三区有奶水| 日本亚洲欧洲另类图片| 朝鲜女子内射杂交bbw| 成人永久免费网站在线观看| 99精品国产兔费观看久久| 97久章草在线视频播放| 97免费人妻在线视频| 中文国产成人精品久久不卡| 亚洲在线国产日韩欧美| 午夜三级a三级三点| 久久人人做人人妻人人玩精品va| 欧美国产精品日韩在线| 欧美黑人与白人精品a片| 99精品国产福利一区二区| 无码人妻丰满熟妇区bbbbxxxx| 一本一本久久a久久精品综合| 久久亚洲精品无码播放| 国产片av片永久免费观看| 亚洲精品久久| 无码人妻丰满熟妇区五十路|